PMID: 15232329Jul 3, 2004Paper

Comparing the effects of 8-week treatment with fluoxetine and imipramine on fasting blood glucose of patients with major depressive disorder

Journal of Clinical Psychopharmacology
Padideh GhaeliSimin Dashti-Khavidaki

Abstract

This study was designed to compare the effects of fluoxetine and imipramine on fasting blood glucose (FBG) in patients with major depressive disorder. Sixty nondiabetic patients with major depressive disorder (based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria) entered this randomized, double-blind study. Patients did not receive any medication affecting serum FBG levels for at least 2 weeks before the initiation of the study. Patients were assigned to receive 20 to 40 mg/d of fluoxetine or 75 to 200 mg/d of imipramine for 8 weeks. Pregnant women and patients with diabetes mellitus and a history of any major heart disease were excluded from this study. Additionally, none of the patients should have received electroconvulsive therapy within 6 months before the initiation of the antidepressants. FBG levels were measured at the initiation, as well as 4 and 8 weeks after starting antidepressants. Nineteen patients in the fluoxetine and 24 patients in the imipramine groups completed the study. In the fluoxetine group, FBG level was decreased from 88.5 mg/dL (baseline) to 85.0 mg/dL at week 4 (P = 0.73), and to 79.8 mg/dL at week 8 (P < 0.001). On the other hand, in the imipramine group, FBG level...Continue Reading

References

Jan 1, 1994·Diabetic Medicine : a Journal of the British Diabetic Association·M O'KaneJ K Wales

❮ Previous
Next ❯

Citations

Apr 14, 2011·International Journal of Clinical Pharmacy·Star Khoza, Jamie C Barner
Sep 10, 2013·Asian Journal of Psychiatry·Pratibha GehlawatVirender Kumar Gehlawat
Jun 27, 2013·Diabetes Research and Clinical Practice·Joana NicolauLluís Masmiquel
Nov 29, 2012·Current Opinion in Psychiatry·Michael Deuschle
Sep 27, 2014·Best Practice & Research. Clinical Endocrinology & Metabolism·Susanne E la Fleur, Mireille J Serlie
Mar 25, 2014·Asian Journal of Psychiatry·Sathya Prakash, Piyali Mandal
Dec 24, 2005·Expert Opinion on Drug Safety·Roger S McIntyreSidney H Kennedy
Mar 4, 2014·Endocrinology and Metabolism Clinics of North America·Alexander BystritskyDavid Kronemyer
Mar 5, 2016·Psychoneuroendocrinology·Marnie G Silverstein-MetzlerThomas C Register
Nov 7, 2015·Reviews in Endocrine & Metabolic Disorders·Giulia RastrelliMario Maggi
Oct 29, 2008·The American Journal of Medicine·Wayne J Katon
Aug 19, 2007·Journal of Psychiatric Research·M Flechtner-MorsH H Ditschuneit
Feb 27, 2007·Journal of Affective Disorders·Yi-Chyan ChenCheng-Hwang Perng
Jul 11, 2014·Journal of Affective Disorders·Jeong Seok SeoWon-Myong Bahk
May 15, 2013·Journal of Affective Disorders·Hui Hua ChangPo See Chen
Oct 17, 2015·British Journal of Pharmacology·Juliane ZemdegsBruno P Guiard
Oct 26, 2016·Acta Neuropsychiatrica·Subethini Roopan, Erik Roj Larsen
Feb 28, 2008·Pharmacoepidemiology and Drug Safety·Hieronymus J DerijksAntoine C Egberts
May 2, 2008·Pharmacoepidemiology and Drug Safety·M J KnolA C G Egberts
Dec 29, 2018·The Journal of Biological Chemistry·Paul Duffield BrewerCynthia Corley Mastick
Nov 12, 2005·Journal of Clinical Psychopharmacology·Hieronymus J DerijksAntoine C G Egberts
Sep 3, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Bianca WilliamsRotonya M Carr
Apr 20, 2018·Journal of Clinical Pharmacy and Therapeutics·F Tillman, J Kim
Jul 9, 2020·Journal of Clinical Psychopharmacology·Hsin-Ya KuoChe-Sheng Chu
Dec 20, 2013·The Cochrane Database of Systematic Reviews·Laura R MagniCorrado Barbui
Feb 17, 2021·The Cochrane Database of Systematic Reviews·Masuma Pervin MishuNajma Siddiqi
Aug 6, 2021·International Journal of Psychiatry in Clinical Practice·Laís Bhering MartinsAntonio Lucio Teixeira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.