Comparing the efficacy of intravenous acetaminophen and intravenous meperidine in pain relief after outpatient urological surgery

Anesthesiology and Pain Medicine
Khosro KolahdouzanSeyed Hossein Ojaghihaghighi

Abstract

Pain relief after surgery is an essential component of postoperative care. The purpose of this study was to compare the efficacy of intravenous acetaminophen and intravenous meperidine in pain relief after outpatient urological surgery. In a prospective, randomized, double-blind clinical trial, 100 outpatients of urological surgery were studied in two groups of acetaminophen (A) and meperidine (M). Patients in group A received 1g of acetaminophen in 100 mL saline within 15 minutes and patients in group M received a single intravenous injection of meperidine 0.5 mg/kg, 15 minutes prior to the end of operation. Postoperative pain was recorded using visual analog scale (VAS). Vital signs, nausea, vomiting, dizziness and respiratory depressions were compared between the two groups. Pain severity in patients treated with intravenous acetaminophen six hours after the operation within one-hour interval was significantly lower than meperidine group (P < 0.0001). Ninety patients in the meperidine group and five patients in the acetaminophen group required additional doses of analgesics. Nausea was significantly lower in acetaminophen group than meperidine group. Intravenous acetaminophen reduced pain following outpatient urological surg...Continue Reading

References

Dec 1, 1981·Acta Anaesthesiologica Scandinavica·I TigerstedtT Tammisto
Jan 5, 2002·Journal of the Royal Army Medical Corps·R Mackenzie, D J Lockey
Nov 19, 2003·The Journal of Pain : Official Journal of the American Pain Society·June L DahlMichael Schurr
Mar 10, 2011·Emergency Nurse : the Journal of the RCN Accident and Emergency Nursing Association·Sara Morgan
Jun 2, 2012·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Chris Pasero, Daphne Stannard
Mar 16, 2013·Anesthesia and Analgesia·Samad E J GolzariKhalil Ansarin
Dec 1, 2012·Current Therapeutic Research, Clinical and Experimental·Pinar ErgenogluAnis Aribogan
Mar 25, 2014·Anesthesiology and Pain Medicine·Samad Ej GolzariAlireza Ala
Apr 5, 2014·Anesthesiology and Pain Medicine·Samad Ej GolzariHanieh Ebrahimi Bakhtavar
May 16, 2014·British Journal of Anaesthesia·D Fletcher, V Martinez
May 16, 2014·Anesthesiology and Pain Medicine·Mahzad AlimianPayman Yazdkhasti
May 16, 2014·Anesthesiology and Pain Medicine·Mahmood EydiZohreh Ostadi

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Methods Mentioned

BETA
cesarean section
hysterectomy

Software Mentioned

Randlist
SPSS

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