Comparing the Prognostic Value of the Eighth Edition of the American Joint Committee on Cancer/Tumor Node Metastasis Staging System Between Papillary and Follicular Thyroid Cancer

Thyroid : Official Journal of the American Thyroid Association
Evert F S van VelsenRobin P Peeters

Abstract

Recently, the eighth edition of the American Joint Committee on Cancer (AJCC)/tumor node metastasis (TNM) staging system for differentiated thyroid cancer (DTC) was published. Studies evaluating this new edition have so far only comprised patients with papillary thyroid cancer (PTC) or made no distinction between PTC and follicular thyroid cancer (FTC). Therefore, this study evaluated the prognostic value of the eighth edition of the AJCC/TNM staging system in a European population with DTC, focusing on potential differences between PTC and FTC. Adult patients with DTC who were diagnosed and/or treated at a Dutch university hospital between January 2002 and April 2016 were retrospectively studied. Overall survival (OS) and disease-specific survival (DSS) were analyzed for DTC and for PTC and FTC separately according to the seventh and eighth editions using the Kaplan-Meier method. Cox's proportional hazards model was used to compare the effect of PTC and FTC on survival. The statistical model performance was assessed using the C-index, Akaike information criterion (AIC), and the Bayesian information criterion. The study included 792 patients with DTC (79% PTC, 21% FTC) with mean age of 49 years. Median follow-up was 7.2 years. ...Continue Reading

References

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Dec 20, 2017·Thyroid : Official Journal of the American Thyroid Association·Miriam ShteinshnaiderCarlos Benbassat

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Citations

May 30, 2019·Thyroid : Official Journal of the American Thyroid Association·Evert F S van VelsenRobin P Peeters
Jan 14, 2020·Thyroid : Official Journal of the American Thyroid Association·Evert F S van VelsenRobin P Peeters
Oct 31, 2019·The Journal of Clinical Endocrinology and Metabolism·Evert F S van VelsenRobin P Peeters
Jan 23, 2020·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Zhengshi WangZhiqiang Yin
Jun 9, 2020·Expert Review of Endocrinology & Metabolism·Firas BaidounOmar Abdel-Rahman
Apr 23, 2020·International Journal of Cancer. Journal International Du Cancer·Malik E JuweidFelix M Mottaghy
Jun 7, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Mu LiAhmad Daniyal Siddiqui
Feb 14, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Dilek YazıcıTarık Terzioğlu
Jun 20, 2020·AJR. American Journal of Roentgenology·Anthony Ciarallo, Juan Rivera
Jan 26, 2021·Thyroid : Official Journal of the American Thyroid Association·Evert F S van VelsenRobin P Peeters
Jun 15, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Ali S AlzahraniR Michael Tuttle

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Methods Mentioned

BETA
dissection

Software Mentioned

survC1
R
DSS
SPSS Statistics

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