Comparing the Success Rate of Dacryocystorhinostomy With and Without Silicone Intubation: A Trial Sequential Analysis of Randomized Control Trials

Scientific Reports
ChuanQi XieShuzhen Li

Abstract

A previous meta-analysis reported no benefit for silicone intubation during dacryocystorhinostomy. However, the power of this meta-analysis was 0.274. Therefore, the benefit of silicone intubation remains controversial. We undertook a cumulative meta-analysis to evaluate the success rate of dacryocystorhinostomy (DCR) with and without the use of a stent. Pubmed, EMBASE and the Cochrane Library were searched. Statistical power and trial sequential analyses were performed according to the result of the meta-analysis. Twelve randomized controlled trials involving 969 cases met the inclusion criteria. The success rates of DCR with and without intubation were significantly different (p = 0.006). The success rates of external DCR (EX-DCR) with and without intubation were also significantly different based on subgroup analysis (p = 0.002). The cumulative z-curves crossed the O'Brian-Fleming boundaries. There were no significant differences in the success rate in the endonasal endoscopic DCR (EN-DCR) subgroup or the occurrence of postoperative complications between the two groups based on the meta-analysis, and the z-curve did not intersect any trial sequential analysis boundaries. DCR with intubation achieved better results than DCR w...Continue Reading

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Citations

Mar 30, 2018·Clinical and Experimental Otorhinolaryngology·Do Hyun KimSe Hwan Hwang
Aug 30, 2018·The Journal of Craniofacial Surgery·Abdullah DalgicDeniz Tuna Edizer
Mar 3, 2020·Ophthalmic Plastic and Reconstructive Surgery·Nandini BothraMohammad Javed Ali
Jul 25, 2020·American Journal of Rhinology & Allergy·Alessandro VinciguerraMatteo Trimarchi
Apr 19, 2020·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Alessandro VinciguerraMatteo Trimarchi
Sep 28, 2020·International Forum of Allergy & Rhinology·Michael YimJeremiah Alt
Aug 12, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Meydan TuranMehmet Fatih Ozhan
May 25, 2018·Orbit·Tarjani Vivek DaveMohammad Javed Ali
Oct 31, 2019·Orbit·Maria Julia OrsoliniAntônio José Maria Catâneo
Sep 30, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Matteo CavaliereArianna Di Stadio

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