Comparing treatment modalities for transplant kidney vesicoureteral reflux in the pediatric population

Journal of Pediatric Urology
K R ShethA Seth

Abstract

Non-refluxing ureteral reimplantation is favored in pediatric renal transplantation to prevent complications, such as vesicoureteral reflux (VUR) in the transplant ureter. VUR resulting in febrile urinary tract infections remains a problem in this population, leading to repeated hospitalizations and increased morbidity. Revision of the vesicoureteral anastomosis can be a surgical challenge due to scar tissue and tenuous vascularity of the transplant ureter. Therefore, alternative options such as endoscopic injection of Deflux at the neo-orifice and surveillance with prophylactic antibiotics have emerged as potential treatment modalities for transplant ureter VUR. The authors reviewed their experience of the management of VUR in the transplant ureter, comparing outcomes of various modalities. With Institutional Review Board approval, a retrospective chart review of all renal transplant patients from January 2002 to January 2017 was conducted. All patients with VUR on voiding cystourethrogram (VCUG) after surgery were identified. Indications for end-stage renal disease, urologic comorbidities, pretransplant VCUG, and operative details were recorded. After transplantation, febrile urinary tract infections, ultrasound findings, and...Continue Reading

Citations

Apr 20, 2021·Frontiers in Pediatrics·Göran LäckgrenAndrew J Kirsch
May 7, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Murat UçarErol Güntekin

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