Comparison and Outcome Analysis of Patients with Takotsubo Cardiomyopathy Triggered by Emotional Stress or Physical Stress

Frontiers in Psychology
Giannakopoulos KonstantinosAkin Ibrahim

Abstract

Background: Previous studies revealed that takotsubo cardiomyopathy (TTC) is triggered by physical and emotional stresses. This study was performed to determine the short- and long-term prognostic impact of emotional- and physical stress associated with TTC. Methods and results: Our institutional database constituted a collective of 84 patients diagnosed with TTC between 2003 and 2015. The patients were divided into two groups as per the presence of emotional stress (n = 24, 21%) or physical stress (n = 60, 52.6%). The endpoint was a composite of in-hospital events (thromboembolic events and life-threatening arrhythmias), myocardial infarction, all-cause of mortality, re-hospitalization due to heart failure, stroke, and recurrence of TTC. A Kaplan-Meier analysis indicated a significantly lower event-free survival rate over a mean follow-up of 5 years in the emotional group than the physical stress group (log-rank, p < 0.01). Multivariate Cox regression analysis revealed only emotional stress (HR 0.4, 95% CI: 0.2-0.9, p < 0.05) as a negative independent predictor of the primary endpoint. Conclusion: Rates of in-hospital events and short- as well as long-term events were significantly lower in TTC patients suffering from emotiona...Continue Reading

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Citations

Jun 26, 2018·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Narut PrasitlumkumThosaporn Boondarikpornpant
Sep 8, 2018·Journal of Insurance Medicine·Tea Mamaladze
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Sep 25, 2020·Deutsche medizinische Wochenschrift·Tillmann SpeerChristian Fastner
Sep 12, 2019·Frontiers in Neurology·Sylvia J BuchmannChristin E Stevens
Aug 10, 2021·The EPMA Journal·Adriana Torres CrignaOlga Golubnitschaja

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