PMID: 9421120Jan 8, 1998Paper

Comparison between a rapid office-based and ELISA serologic test in screening for Helicobacter pylori in children

Helicobacter
Y ElitsurW E Triest

Abstract

The rapid diagnostic serological test for detection of Helicobacter pylori (H. pylori) infection in children has a significant advantage over the standard enzyme immunoassay (EIA) method, for its simplicity and rapid availability of results in a physician's office setting. We compared the immunochromatographic test with a standard enzyme immunoassay test in the pediatric population. A retrospective analysis of 1147 serum samples from asymptomatic children and prospective analysis of 62 serum samples from symptomatic children undergoing diagnostic upper endoscopy were evaluated for the detection of H. pylori antibody by two commercially available serology tests. Each serum sample was tested by a rapid test (FlexSure HP, SmithKline Diagnostics, Inc.) and compared to the standard EIA method (HM-CAP, Enteric Products, Inc.). The rapid test, FlexSure HP, was comparable to the rapid EIA test in screening for H. pylori infection in symptomatic and asymptomatic children with sensitivity and specificity of 83-90% and 90-100%, respectively. Both methods had a comparable sensitivity and specificity for the detection of H. pylori-associated gastritis (60-70% and 94%, respectively). The rapid test is comparable to the standard EIA test and ...Continue Reading

References

May 1, 1991·Journal of Gastroenterology and Hepatology·A B Price
May 1, 1996·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J RaymondC Dupont

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Citations

Mar 29, 2000·Alimentary Pharmacology & Therapeutics·B C WongS Lam
Sep 9, 1999·Journal of Clinical Gastroenterology·Y ElitsurC Neace
Feb 5, 1999·Journal of Pediatric Gastroenterology and Nutrition·S J Czinn
Sep 21, 2001·European Journal of Gastroenterology & Hepatology·S Koletzko, A Feydt-Schmidt
Feb 4, 2005·The Journal of Pediatrics·Yoram Elitsur
Oct 16, 1999·The American Journal of Gastroenterology·W K LeungJ J Sung
Mar 16, 2018·The Cochrane Database of Systematic Reviews·Lawrence Mj BestKurinchi Selvan Gurusamy
Jul 4, 2013·The American Journal of Gastroenterology·Yoram Elitsur
Jan 17, 2002·Journal of Clinical Laboratory Analysis·R M Nakamura
Jan 13, 2006·Journal of Tropical Pediatrics·Suporn TreepongkarunaPrapun Aanpreung
Oct 12, 2001·Current Problems in Pediatric and Adolescent Health Care·B D Gold
Oct 17, 1998·Journal of Clinical Microbiology·W K LeungJ J Sung

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