Comparison between an intradermal skin test and allergen-specific IgE-ELISA for canine atopic dermatitis

Schweizer Archiv für Tierheilkunde
N TarpatakiK Vörös

Abstract

The aim of this study was to compare the results of an intradermal skin test (IDST) with those of an allergen-specific IgE-ELISA in 210 dogs with atopic dermatitis. All the dogs had a clinical diagnosis of atopic dermatitis and underwent an IDST. The sera of all dogs were analysed for allergen-specific IgE by ELISA using the monoclonal antibody D9 against dog IgE. IDST was used as the standard assay. In both methods, the following antigens provided a positive test result: Dermatophagoides farinae, Acarus siro, Tyrophagus putrescentiae, ragweed, mugwort and Lepidoglyphus destructor. ELISA had an overall sensitivity of 82.4% and an overall specificity of 93.8%. The overall accuracy of the ELISA was 91.3%. The evaluated monoclonal D9 ELISA was found to be a reliable tool for the diagnosis of those allergens that cause clinical atopy, and can be recommended for use in dogs when immunotherapy is a therapeutic option.

Citations

Mar 22, 2012·Veterinary Dermatology·Stefanie KoebrichClaude Favrot
Jun 10, 2015·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Andrea L Goodnight
Dec 5, 2020·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Amirhossein MohammaddavoodiRegina Wagner
May 19, 2021·Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·Amirhossein MohammaddavoodiRegina Wagner

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