Comparison between computed tomography-guided percutaneous microwave ablation and thoracoscopic lobectomy for stage I non-small cell lung cancer

Thoracic Cancer
Yongzheng WangYuliang Li

Abstract

The study was conducted to investigate the effectiveness and cost of computed tomography (CT)-guided percutaneous microwave ablation (MWA) and thoracoscopic lobectomy for stage I non-small cell lung cancer (NSCLC). We retrospectively analyzed the data of 46 and 85 patients with stage I NSCLC treated with CT-guided percutaneous MWA or thoracoscopic lobectomy, respectively, at our center from July 2013 to June 2015. Overall survival (OS), disease-free survival (DFS), local control rate, hospital stay, and cost were evaluated. Survival curves were constructed using the Kaplan-Meier method and compared using the log-rank test. The one and two-year OS rates were 97.82% and 91.30% and 97.65% and 90.59% in the MWA and lobectomy groups, respectively. The one and two-year DFS rates were 95.65% and 76.09% and 95.29% and 75.29%, respectively. No significant differences were observed in log-rank analysis between the groups (P = 0.169). The hospital stays in the MWA and lobectomy groups were 6.62 ± 2.31 and 9.57 ± 3.19 days, respectively. The costs of MWA and lobectomy were US$3274.50 ± US$233.91 and US$4678.87 ± US$155.96, respectively. The differences were all significant (P = 0.003). MWA and thoracoscopic lobectomy for stage I NSCLC demo...Continue Reading

References

Dec 1, 1989·Cancer Treatment Reviews·J G Armstrong, B D Minsky
Oct 20, 1993·International Journal of Radiation Oncology, Biology, Physics·L KaskowitzC Rush
Nov 4, 1998·Seminars in Thoracic and Cardiovascular Surgery·A P YimC C Ma
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Branislav JeremicMichael Bamberg
Mar 5, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Wilson W L LiAnthony P C Yim
Aug 23, 2005·Expert Review of Anticancer Therapy·Caroline J Simon, Damian E Dupuy
Aug 24, 2005·International Journal of Radiation Oncology, Biology, Physics·Ronald C McGarryRobert D Timmerman
Apr 25, 2007·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Alex G LittleAndrew K Stewart
Dec 23, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E A EisenhauerJ Verweij
Jan 25, 2012·Cardiovascular and Interventional Radiology·Philippe L PereiraUNKNOWN Cardiovascular and Interventional Radiological Society of Europe (CIRSE)
May 17, 2014·Primary Care·Thomas B RichardsRalph S Caraballo
Jul 24, 2014·Seminars in Interventional Radiology·Carol A RidgeRaymond H Thornton
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Jun 2, 2015·Clinical Lung Cancer·Guy C JonesAradhana Kaushal

❮ Previous
Next ❯

Citations

Oct 18, 2019·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Zhigang WeiXiaoying Han
Sep 25, 2020·Asia-Pacific Journal of Clinical Oncology·Yang NiXin Ye
Aug 7, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Paul HabertJean-Yves Gaubert

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
dissection

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Vascular and Interventional Radiology : JVIR
Claudio PuscedduLuca Melis
International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Wang YaoZhihua Zhu
Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Apar PataerUniversity of Texas M. D. Anderson Lung Cancer Collaborative Research Group
© 2022 Meta ULC. All rights reserved