Comparison between fine-needle biopsy and fine-needle aspiration for EUS-guided sampling of subepithelial lesions: a meta-analysis

Gastrointestinal Endoscopy
Antonio FacciorussoNicola Muscatiello

Abstract

There is limited evidence on the diagnostic performance of EUS-guided fine-needle biopsy (FNB) sampling in patients with subepithelial lesions. The aim of this meta-analysis was to compare EUS-guided FNB sampling performance with FNA in patients with GI subepithelial lesions. A computerized bibliographic search on the main databases was performed through May 2019. The primary endpoint was sample adequacy. Secondary outcomes were diagnostic accuracy, histologic core procurement rate, and mean number of needle passes. Summary estimates were expressed in terms of odds ratio (OR) and 95% confidence interval (CI). Ten studies (including 6 randomized trials) with 669 patients were included. Pooled rates of adequate samples for FNB sampling were 94.9% (range, 92.3%-97.5%) and for FNA 80.6% (range, 71.4%-89.7%; OR, 2.54; 95% CI, 1.29-5.01; P = .007). When rapid on-site evaluation was available, no significant difference between the 2 techniques was observed. Optimal histologic core procurement rate was 89.7% (range, 84.5%-94.9%) with FNB sampling and 65% (range, 55.5%-74.6%) with FNA (OR, 3.27; 95% CI, 2.03-5.27; P < .0001). Diagnostic accuracy was significantly superior in patients undergoing FNB sampling (OR, 4.10; 95% CI, 2.48-6.79;...Continue Reading

Citations

Mar 13, 2020·Minerva gastroenterologica e dietologica·Antonio Facciorusso
Jul 14, 2020·Endoscopic Ultrasound·Bojan Kovacevic, Peter Vilmann
Sep 6, 2020·Current Opinion in Gastroenterology·Thomas R McCarty, Marvin Ryou
Nov 5, 2020·Diagnostics·Masahiro ItonagaMasayuki Kitano
Jan 28, 2021·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·José Celso ArdenghJosé Sebastião Dos Santos
Jul 18, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Christine LefortBertrand Napoléon
Jul 25, 2020·Current Drug Metabolism·Manuele FurnariLeonardo Henry Eusebi
Mar 19, 2021·European Journal of Gastroenterology & Hepatology·Inês PitaPedro Bastos

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