PMID: 7017781Feb 1, 1981Paper

Comparison between fluproquazone and indomethacin in treatment of primary dysmenorrhoea

Prostaglandins and Medicine
O YlikorkalaA Kauppila

Abstract

Two prostaglandin synthesis inhibitors, fluproquazone (100 mg) and indomethacin (25 mg), were compared in a double-blind, crossover study for treatment of primary dysmenorrhoea in 31 patients. Each drug was used during two consecutive menstruations in randomized order. Both treatments significantly relieved spasmodic pains and other dysmenorrhoeic symptoms. No significant differences were found between the treatments in regard to the overall efficacy assessed at the end of each treated cycle. However, 20 patients preferred indomethacin and 7 patients fluproquazone. Three patients reported mild side-effects with fluproquazone as compared to five patients wih indomethacin. It is concluded that both treatments can be used for treatment of primary dysmenorrhoea.

References

Apr 1, 1978·American Journal of Obstetrics and Gynecology·O Ylikorkala, M Y Dawood
Feb 18, 1978·Lancet·A B AndersonA C Turnbull
Apr 15, 1977·American Journal of Obstetrics and Gynecology·M R HenzlS Bessler
Sep 1, 1977·Obstetrical & Gynecological Survey·M R HenziS Bessler
Jan 1, 1979·Acta Obstetricia Et Gynecologica Scandinavica. Supplement·P Kajanoja, T Vesanto
Oct 1, 1979·Prostaglandins·A KauppilaO Ylikorkala
May 1, 1976·Prostaglandins·V LundströmN Wiqvist
Apr 1, 1980·British Journal of Obstetrics and Gynaecology·J R Pogmore, G M Filshie
Apr 1, 1965·The Journal of Obstetrics and Gynaecology of the British Commonwealth·V R PICKLESG N SMITH

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Citations

Jan 1, 1984·Archives of Gynecology·H P Zahradnik, M Breckwoldt
Sep 1, 1986·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A KauppilaA Seppälä
Aug 1, 2015·The Cochrane Database of Systematic Reviews·Jane MarjoribanksMichelle Proctor
Jul 1, 1985·Acta Physiologica Scandinavica·S MaigaardK E Andersson

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