Comparison between malignant and nonmalignant splenic masses in dogs using contrast-enhanced computed tomography

Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Wendy D FifeStacy Hoshaw-Woodard

Abstract

The ability of computed tomography (CT) to distinguish malignant from nonmalignant splenic masses was evaluated in 21 dogs with 24 masses. CT scans of the abdomen were performed pre- and postintravenous contrast medium administration before splenectomy or euthanasia. Splenic masses were evaluated objectively based on Hounsfield units (HU) and volume. Subjective criteria included location within the spleen (head, body, or tail), margination, homogeneity, and attenuation compared to the remaining splenic parenchyma. Characteristics of malignant and nonmalignant masses were compared. The nonmalignant masses were divided into splenic hematomas and nodular hyperplasia for further analysis. Fourteen (58.3%) of the masses were nonmalignant; 10 (41.7%) were malignant. Malignant splenic masses had significantly lower attenuation values, measured in HU, than nonmalignant splenic masses, on both pre- and postcontrast images (P<0.05). On postcontrast images, there was a significant difference in attenuation characteristics among all three subsets of splenic masses (malignant, hematoma, hyperplasia), with nodular hyperplasia having the highest HU values (90.3), hematomas having intermediate HU values (62.5), and malignant splenic masses hav...Continue Reading

References

Jul 1, 1989·Journal of Veterinary Internal Medicine·K A JohnsonR H Wrigley
Sep 1, 1985·The British Journal of Radiology·J M Wafula
Jun 1, 1980·Radiology·J PiekarskiS S London
Oct 1, 1995·The Journal of Small Animal Practice·M J DayH Pearson
May 1, 1996·AJR. American Journal of Roentgenology·F FerrozziG Garlaschi
May 1, 1997·Journal of Veterinary Internal Medicine·W L Spangler, P H Kass
Apr 8, 1998·AJR. American Journal of Roentgenology·B A Urban, E K Fishman
Jan 1, 1996·Radiographics : a Review Publication of the Radiological Society of North America, Inc·M UrrutiaP R Ros
Aug 30, 2000·Southern Medical Journal·S C Reddy, S C Reddy
Feb 24, 2001·European Radiology·F RobertsonO Ekberg
Jun 19, 2001·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·M N PatsikasA K Dessiris

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Aug 7, 2008·Journal of Veterinary Internal Medicine·S OhlerthB Kaser-Hotz
Nov 3, 2010·Journal of Veterinary Internal Medicine·K NakamuraM Takiguchi
Feb 19, 2008·Journal of the American Veterinary Medical Association·Tara N Hammond, S Anna Pesillo-Crosby
Nov 3, 2011·Journal of the American Veterinary Medical Association·Mary Jo Mallinckrodt, Sharon D Gottfried
Feb 8, 2016·The Veterinary Clinics of North America. Small Animal Practice·Lisa J Forrest
Jan 15, 2016·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Ian D JonesPanagiotis Mantis
Jul 22, 2015·The Journal of Veterinary Medical Science·Mijin KimKija Lee
Oct 24, 2007·The Veterinary Clinics of North America. Small Animal Practice·Amy K LeBlanc, Gregory B Daniel
Sep 23, 2009·The Journal of Small Animal Practice·N WenzlowK C Smith
Apr 19, 2008·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Federica RossiRossella Terragni
Jan 13, 2012·Veterinary and Comparative Oncology·D H ThammK A Selting
May 23, 2012·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Erica L FieldsJames C Brown
Aug 8, 2013·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Miriam M ShanamanRobert T O'Brien
Sep 19, 2012·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Seamus HoeyScott Hetzel
Jan 3, 2014·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Shoko FukudaDonald E Thrall
Feb 20, 2010·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Kensuke NakamuraMitsuyoshi Takiguchi
Jun 13, 2006·The Veterinary Journal·Marcio TeixeiraAmalia Agut
Mar 7, 2006·The Veterinary Journal·Stefanie Ohlerth, Gernot Scharf
Sep 4, 2015·Journal of the American Veterinary Medical Association·Alex M LynchJessie Hamilton
Jul 3, 2013·The Veterinary Journal·John S Mattoon, Jeffrey N Bryan
May 4, 2017·Journal of the American Veterinary Medical Association·Erin E CorbinTaryn Donovan
Oct 11, 2017·The Journal of Veterinary Medical Science·Kenji KutaraKazushi Asano
Sep 25, 2018·Veterinary Surgery : VS·Jeremy FlemingSteven E Epstein
Jun 25, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Alessia CordellaGiovanna Bertolini
Feb 21, 2019·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jonathan R HughesRandi Drees
Sep 4, 2018·Journal of Veterinary Science·Mokhyeon LeeSeong Mok Jeong
Feb 23, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Jonathan R HughesMarie-Aude Genain
Nov 4, 2020·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Olga AmorósRosa Novellas
Apr 21, 2021·Veterinary and Comparative Oncology·Jennifer KelseyPhilip H Kass
Jul 3, 2021·The Veterinary Record·Maureen A GriffinRobert B Rebhun

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