Comparison between remifentanil and dexmedetomidine for sedation during modified awake fiberoptic intubation

Experimental and Therapeutic Medicine
Hui-Hui LiuWu-Hua Ma

Abstract

Cricothyroid membrane injections and the application of a coarse fiberoptic bronchoscope (FOB) below the vocal cords for topical anesthesia have a number of limitations for certain patients. Thus, the aim of the present observational study was to assess the effect of a novel modified topical anesthesia method using the effective sedation drugs, remifentanil (Rem) or dexmedetomidine (Dex), during awake fiberoptic orotracheal intubation (AFOI). In total, 90 adult patients, who had been classified as American Society of Anesthesiologists I-II, were included in the study. The patients had anticipated difficult airways and were to undergo orotracheal intubation for elective surgery. The patients were enrolled in the double-blinded randomized pilot study and received Rem or Dex for sedation during the modified AFOI procedure. The two groups received 2% lidocaine for topical anesthesia via an epidural catheter, which was threaded through the suction channel of the FOB. The main clinical outcomes were evaluated by graded scores representing the conditions for intubation and post-intubation. Additional parameters analyzed included airway obstruction, hemodynamic changes, time required for intubation, amnesia level and subjective satisfa...Continue Reading

References

Apr 29, 2000·Acta Anaesthesiologica Scandinavica·P KundraM Ravishankar
Jun 27, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Corey S Scher, Melvin C Gitlin
Mar 24, 2007·Journal of Clinical Anesthesia·Sergio D BergeseMark A Gerhardt
Nov 3, 2010·Veterinary Anaesthesia and Analgesia·Christine A BoehmRonald P Wilson

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Citations

Sep 9, 2015·Journal of Clinical Anesthesia·Chao SunGao-Pu Liu
Apr 26, 2016·Anesthesiology·Thomas T JosephJaime B Hyman
Dec 5, 2019·National Journal of Maxillofacial Surgery·Arun KumarGyan Prakash Singh

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Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

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