COMPARISON BETWEEN SEVERAL OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DEVICES AND INDOCYANINE GREEN ANGIOGRAPHY OF CHOROIDAL NEOVASCULARIZATION.

Retina
Federico CorviAndrea Giani

Abstract

To compare indocyanine green angiography and four different optical coherence tomography angiography (OCTA) devices and to test their reproducibility in the evaluation of choroidal neovascularization (CNV). This study was an observational case series of Type 1 and Type 2 CNV presenting at the Eye Clinic, Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, University of Milan, imaged with indocyanine green angiography and four different OCTA devices: prototype PlexElite (Carl Zeiss Meditec), prototype Spectralis OCTA (Spectralis; Heidelberg Engineering, Heidelberg, Germany), Optovue RTVue XR Avanti (Optovue, Inc, Fremont, CA), and AngioPlex (Cirrus 5000 HD-OCT; Carl Zeiss Meditec, Inc, Dublin, CA). Optical coherence tomography angiography examinations were performed using a 3 × 3-mm or 6 × 6-mm volume scan pattern to capture the full lesion. The mean area of CNV, vessel density, and fractal dimension were compared between the devices. Seventeen eyes of 17 patients with CNV were enrolled. The CNV area was significantly larger in indocyanine green angiography than in the OCTA devices. Moreover, the four different instruments produced measurements with different mean values of CNV area, vessel density, and fractal...Continue Reading

References

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Citations

Feb 28, 2019·Investigative Ophthalmology & Visual Science·Hongli YangClaude F Burgoyne
Oct 14, 2020·Eye·Federico CorviSrinivas R Sadda
Oct 17, 2020·Translational Vision Science & Technology·Federico CorviSriniVas R Sadda
Oct 27, 2020·Translational Vision Science & Technology·Rodolfo MastropasquaLisa Toto
Mar 7, 2021·Journal of Clinical Medicine·Jackson ScharfDavid Sarraf
Dec 16, 2021·Ophthalmic Surgery, Lasers & Imaging Retina·Federico CorviSriniVas R Sadda

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