Comparison between Sigma metrics in four accredited Egyptian medical laboratories in some biochemical tests: an initiative towards sigma calculation harmonization

Biochemia Medica
Rania El SharkawyEman Shaheen

Abstract

Analytical quality is an essential requirement for best practice in any medical laboratory. Lack of a harmonized approach for sigma calculation is considered an obstacle in the objective comparability of analytical performance among laboratories adopting sigma metrics. It is urgently needed that all laboratory professionals interested in the analytical quality to work hard towards harmonization protocol for sigma calculation in order to properly select their analytical goals. This study aims at harmonization of Sigma metrics calculation in four accredited Egyptian laboratories. This observational cross sectional study compared the sigma levels for certain biochemical parameters in the four participating laboratories. Coefficient of variation (CV) and bias were determined for some biochemical analytes, data assayed by different automated analysers in the four different accredited laboratories. The sigma level for the four medical laboratories was calculated for each biomedical parameter with changed sigma level after total allowable error (Tea) unification among participating laboratories. Each laboratory should select the TEa goal based on clear standardized criteria of selection without any subjective preferences as either und...Continue Reading

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Citations

Mar 7, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Martine J HollestelleMoniek P M de Maat
Jul 20, 2018·Biochemia Medica·Sten WestgardJames O Westgard
Jul 19, 2021·International Journal of Laboratory Hematology·Wafaa Ahmed El-NeanaeyReham Abdel Haleem Abo Elwafa

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