Comparison between skeletal muscle and adipose tissue measurements with high-dose CT and low-dose attenuation correction CT of 18F-FDG PET/CT in elderly Hodgkin lymphoma patients: a two-centre validation.

The British Journal of Radiology
Domenico AlbanoFrancesco Bertagna

Abstract

High-dose CT (HDCT) is considered the gold-standard imaging for the measurements of skeletal muscle area (SMA), visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT) and intramuscular adipose tissue (IMAT) areas in the abdomen. These parameters may reflect sarcopenia, which can have a prognostic impact in several oncological diseases. The aim of this study was to compare the agreement of measurements of SMA, VAT, SAT and IMAT areas between HDCT and low-dose CT (LDCT) of 18-fludeoxyglucose positron emission tomography (18F-FDG PET)/CT in elderly patients affected by Hodgkin lymphoma (HL). We retrospectively included 90 patients affected by HL who underwent baseline 18F-FDG-PET/CT and HDCT within a mean interval of 7 days. HDCT and LDCT images were analysed by two blinded observers using segmentation software (Slice-O-Matic, Tomovision) to quantify the areas. HDCT and LDCT measurements were compared using Bland-Altman plots and Passing-Bablock regression analyses. Pearson correlation coefficient (r) was used to correlate measurements from the two imaging modalities. Comparison of HDCT and LDCT data demonstrated a strong correlation for measurement of VAT(r = 0.942, p < 0.0001), SAT (r = 0.894, p < 0.0001) and SMA (r = ...Continue Reading

References

Apr 6, 2000·Journal of Applied Physiology·W R FronteraR Roubenoff
Apr 6, 2005·Current Opinion in Clinical Nutrition and Metabolic Care·Lindsay D Plank
Oct 9, 2007·The American Journal of Clinical Nutrition·Ross D HansenMaria A Fiatarone Singh
Feb 8, 2011·The Lancet Oncology·Kenneth FearonVickie E Baracos
Dec 14, 2011·Physics in Medicine and Biology·Ting XiaPaul E Kinahan
Apr 20, 2012·The British Journal of Radiology·B J KlopfensteinJ Q Purnell
Jul 12, 2013·Calcified Tissue International·C CooperJ A Kanis
Apr 17, 2014·Clinical Physiology and Functional Imaging·Marie Ø Fosbøl, Bo Zerahn
Aug 13, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bruce D ChesonT Andrew Lister
Aug 13, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sally F BarringtonBruce D Cheson
Dec 3, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Ronald BoellaardUNKNOWN European Association of Nuclear Medicine (EANM)
Sep 20, 2015·Annals of Hematology·Nobuhiko NakamuraHisashi Tsurumi
Sep 27, 2016·European Journal of Radiology·Andrey SinelnikovAlessandro Furlan
Apr 19, 2017·Clinical Physiology and Functional Imaging·Anne van der WerfJacqueline A E Langius
Jul 27, 2017·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Jeroen L A van VugtFrançois E J A Willemsen
Oct 13, 2018·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2
Apr 4, 2019·British Journal of Haematology·Madelyn BurkartReem Karmali
Apr 22, 2020·Journal of Cachexia, Sarcopenia and Muscle·Elizabeth M Cespedes FelicianoBette J Caan

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