Comparison between stimulated in-vitro fertilization and stimulated intrauterine insemination for the treatment of unexplained and mild male factor infertility

Human Reproduction
F ZayedI D Cooke

Abstract

A prospective trial was undertaken to evaluate the efficacy of stimulated in-vitro fertilization (SIVF) and stimulated intrauterine insemination (SIUI) in couples with unexplained and mild male factor infertility. In all, 80 couples were allocated to treatment with SIVF or SIUI, both treatments following the same protocol [clomiphene citrate and follicle stimulating hormone (FSH) injection], except that higher doses of FSH were used in the SIVF treatment cycles. Initially, 41 couples were allocated to and started treatment with SIVF but eight cases were eventually converted to SIUI because of under-response. Similarly, although 39 couples were initially allocated to SIUI treatment, five of these converted to SIVF because of over-response. The treatment cycles that were converted either to SIUI or to SIVF were not considered as treatment failures but as treatment changes and so were included in the analyses. Of the final 38 SIVF cycles, four were cancelled (dysfunctional response), failed fertilization occurred in five cycles and 29 subjects reached embryo transfer. There were two biochemical pregnancies [positive human chorionic gonadotrophin (HCG) only], two clinical abortions and seven live births. Of the final 42 SIUI cycles...Continue Reading

Citations

May 12, 2004·Fertility and Sterility·Gilberto IbéricoRafael Bernabeu
Oct 16, 1999·Fertility and Sterility·G RagniP G Crosignani
Sep 30, 2008·Human Reproduction Update·Willem OmbeletPaul Devroey
Feb 9, 1999·Obstetrical & Gynecological Survey·F Zayed, A Abu-Heija
Dec 17, 2009·Obstetrics and Gynecology International·Abdelrahman M Abdelkader, John Yeh
Sep 14, 2004·Gynecologic and Obstetric Investigation·F J Broekmans, E R Klinkert
Jun 2, 2011·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·B DemirU Goktolga
Jul 19, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Young Eun JeonByung Seok Lee
Dec 29, 2004·Human Fertility : Journal of the British Fertility Society·Elizabeth A Lenton
Oct 27, 2004·Gynécologie, obstétrique & fertilité·D Royère
Aug 28, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Alexandra J BensdorpUNKNOWN INeS group
Jul 26, 2011·Fertility and Sterility·Stefan SchanzGerhard Fierlbeck
Oct 30, 2016·Acta Biochimica Et Biophysica Sinica·Jianbing LiuZhugang Wang
Nov 20, 2015·The Cochrane Database of Systematic Reviews·Zabeena PandianSiladitya Bhattacharya
Jan 6, 2006·Obstetrics and Gynecology·Bradley J Van Voorhis
Sep 6, 2019·The Cochrane Database of Systematic Reviews·Rui WangMadelon van Wely
Jan 22, 2003·The Cochrane Database of Systematic Reviews·A E CantineauB J Cohlen
Feb 27, 2016·The Cochrane Database of Systematic Reviews·Maartje CissenMadelon van Wely

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