Comparison between thromboelastography and conventional coagulation test: Should we abandon conventional coagulation tests in polytrauma patients?

Cirugía española
Jaume Tur MartínezCorrado P Marini

Abstract

TEG provides an in-vivo assessment of viscoelastic clot strength in whole blood compared with CCT, which may not reflect the influence of platelets. The aim of this study was to compare TEG vs. CCT in trauma patients stratified by mechanism of injury (MOI) and pre-existing coagulation status. A retrospective, observational study of 230 polytrauma patients admitted to a University Hospital Level 1 Trauma Center, with TEG and CCT on admission stratified by MOI: multiple trauma (MT), isolated traumatic brain injury (TBI) or MT+TBI. Statistical analysis included correlation between TEG and CCT in all groups and a subgroup analysis of anticoagulated patients. Data were analyzed with ANOVA, Spearman and lineal regression when appropriate. Statistical significance was accepted at P<0.05. TEG was normal in 28.7%, hypercoagulable in 68.3%, hypocoagulable in 7%. There was no difference in TEG status among the groups. The coagulation status was not affected by age, ISS or shock. The CCT were abnormal in 63.6% of patients with normal TEG. Normal or hypercoagulable-TEG was found in 21/23 patients on Coumadin who had elevated INR and in 10/11 patients on NOAC. An analysis of the 23 patients on Coumadin stratified by INR showed a normal or hy...Continue Reading

Citations

Jan 30, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Marco GianiGiuseppe Foti
Apr 13, 2021·Military Medical Research·Jing-Chun SongUNKNOWN Chinese People’s Liberation Army Professional Committee of Critical Care Medicine and Chinese Society of Thrombosis, Hemosta

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