PMID: 6166272Feb 1, 1981Paper

Comparison in genetically hyperlipoproteinemic and normal rats of the secretion of lipids synthesized by isolated livers perfused with isotopic oleic acid and glycerol at high concentrations

Archives internationales de physiologie et de biochimie
F ChanussotG Debry

Abstract

After perfusing isolated livers of Zucker fa/fa ad Fa/- rats with loads of [9,10-3H2] oleic acid (346 mumol) and [1-14C] glycerol (115 mumol), glycerol inhibited the hepatic secretion of triacylglycerol and phospholipids in the two groups of rats. However, the amount of acylglycerols synthetized from these exogenous substrates is slightly higher in the obese rats than in the normal rats. These results suggest that glycerol, present in high amounts in blood of fa/fa rats, failed to regulate triacylglycerols and phospholipids secretion.

References

Jun 22, 1976·Biochimica Et Biophysica Acta·D PetitR Infante
Oct 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·L B Gardner, S Reiser
Jan 1, 1976·Biochemical Society Transactions·P A Mayes
Jan 1, 1978·Proceedings of the Society for Experimental Biology and Medicine·C D BerdanierR Wurdeman
May 1, 1968·Biochimica Et Biophysica Acta·K C RichardsM G Herrera
Dec 8, 1962·Nature·P B GARLAND, P J RANDLE
Oct 1, 1951·Proceedings of the Society for Experimental Biology and Medicine·R W BRAUERP PIZZOLATO

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