Comparison of a Significant Decline in the Glomerular Filtration Rate between Ileal Conduit and Ileal Neobladder Urinary Diversions after Radical Cystectomy: A Propensity Score-Matched Analysis

Journal of Clinical Medicine
Jihion YuYoung-Kug Kim

Abstract

Urinary diversion after radical cystectomy is associated with a risk of renal function impairment. A significant decline in the glomerular filtration rate (GFR) (i.e., a ≥30% decline in baseline GFR after 12 months) is associated with long-term renal function impairment. We compared the significant GFR decline between ileal conduit and ileal neobladder urinary diversions 12 months after radical cystectomy. We retrospectively included radical cystectomy patients. Propensity score-matched analysis was performed. The primary outcome was the incidence of a significant GFR decline in ileal conduit urinary diversion (ileal conduit group) and ileal neobladder urinary diversion (ileal neobladder group) 12 months after radical cystectomy. The secondary outcomes were the change of GFR and the incidence of end-stage renal disease (ESRD) in the two groups. After propensity score matching, the ileal conduit and neobladder groups had 117 patients each. The incidence of a significant GFR decline was not significantly different between ileal conduit and ileal neobladder groups (12.0% vs. 13.7%, p = 0.845). The change of GFR and ESRD incidence were not significantly different between the two groups (-8.4% vs. -9.7%, p = 0.480; 4.3% vs. 5.1%, p ...Continue Reading

References

Dec 10, 1997·The Urologic Clinics of North America·U E Studer, E J Zingg
Oct 1, 1950·The Surgical Clinics of North America·E M BRICKER
Nov 23, 2006·Journal of the American College of Surgeons·Florence E TurrentineR Scott Jones
Oct 22, 2008·The Journal of Urology·Brian R LaneAndrew C Novick
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Jun 13, 2009·Lancet·Donald S KaufmanAdam S Feldman
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
Oct 15, 2010·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Andrea G LantzIlias Cagiannos
Dec 21, 2010·The Journal of Urology·Mark S ShimkoIgor Frank
Apr 19, 2011·The Journal of Urology·In Gab JeongChoung-Soo Kim
Apr 19, 2011·The Journal of Urology·Richard E HautmannBjoern G Volkmer
Mar 8, 2012·World Journal of Urology·In Gab JeongChoung-Soo Kim
Sep 22, 2012·European Urology·Richard E HautmannUNKNOWN International Consultation on Urologic Disease-European Association of Urology Consultation on Bladder Cancer 2012
May 31, 2013·Current Opinion in Supportive and Palliative Care·Bassel G Bachir, Wassim Kassouf
Sep 17, 2013·The Journal of Urology·Manuel S EisenbergStephen A Boorjian
Dec 3, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Hiddo J Lambers HeerspinkLesley A Inker
Dec 3, 2014·The Journal of Urology·Joseph R ZabellChristopher J Weight
Aug 19, 2015·International Journal of Medical Sciences·Kyoung-Woon JoungYoung-Kug Kim
Oct 21, 2018·BMJ : British Medical Journal·James GilbertUNKNOWN Guideline Committee

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.