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Comparison of alignment software for genome-wide bisulphite sequence data

Nucleic Acids Research

Feb 22, 2012

Aniruddha ChatterjeeIan M Morison

Abstract

Recent advances in next generation sequencing (NGS) technology now provide the opportunity to rapidly interrogate the methylation status of the genome. However, there are challenges in handling and interpretation of the methylation sequence data because of its large volume and the conse...read more

Mentioned in this Paper

Protein Methylation
DNA Methylation
Computer Programs and Programming
Genomics
Sodium bisulfite
Sequencing
Massively-Parallel Sequencing
Methylation
Sequence Determinations, DNA
Sulfites
3
1
201
Paper Details
References
  • References15
  • Citations38
12
  • References15
  • Citations38
1234

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Comparison of alignment software for genome-wide bisulphite sequence data

Nucleic Acids Research

Feb 22, 2012

Aniruddha ChatterjeeIan M Morison

PMID: 22344695

DOI: 10.1093/nar/gks150

Abstract

Recent advances in next generation sequencing (NGS) technology now provide the opportunity to rapidly interrogate the methylation status of the genome. However, there are challenges in handling and interpretation of the methylation sequence data because of its large volume and the conse...read more

Mentioned in this Paper

Protein Methylation
DNA Methylation
Computer Programs and Programming
Genomics
Sodium bisulfite
Sequencing
Massively-Parallel Sequencing
Methylation
Sequence Determinations, DNA
Sulfites
3
1
201

Similar Papers Found In These Feeds

Non-coding Variants in Cancer

Mutations, single nucleotide variants and large genomic rearrangements, in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. Here is the latest research.

Non-coding Variants in Cancer (Keystone)

Mutations, single nucleotide variants and large genomic rearrangements in non-coding regions of the genome can have severe consequences such as disruption of transcription factor binding sites and functions of non-coding RNAs and can impact tumor development and progression. This feed focuses on the latest research on non-coding variants in cancer.

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Bioinformatics

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

BioinformaticsApril 16, 2011
Felix Krueger, Simon R Andrews
Paper Details
References
  • References15
  • Citations38
12
  • References15
  • Citations38
1234
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