Comparison of anesthetic depth indexes based on thalamocortical local field potentials in rats

Anesthesiology
Aura SilvaLuis M Antunes

Abstract

Local field potentials may allow a more precise analysis of the brain electrical activity than the electroencephalogram. In this study, local field potentials were recorded in the thalamocortical axis of rats to (i) compare the performance of several indexes of anesthetic depth and (ii) investigate the existence of thalamocortical correlated or disrupted activity during isoflurane steady-state anesthesia. Five rats chronically implanted with microelectrodes were used to record local field potentials in the primary somatosensory cortex and ventroposterolateral thalamic nuclei at six periods: before induction of anesthesia; in the last 5 min of randomized 20-min steady-state end-tidal 0.8, 1.1, 1.4, and 1.7% isoflurane concentrations; and after recovery. The approximate entropy, the index of consciousness, the spectral edge frequency, and the permutation entropy were estimated using epochs of 8 s. A correction factor for burst suppression was applied to the spectral edge frequency and to the permutation entropy. The correlation between the derived indexes and the end-tidal isoflurane was calculated and compared for the two studied brain regions indexes. Coherence analysis was also performed. The burst suppression-corrected permut...Continue Reading

References

Jul 31, 1998·Journal of Sleep Research·P Achermann, A A Borbély
Oct 20, 1998·Anesthesiology·I J Rampil
Mar 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·M Steriade
Sep 29, 2001·Trends in Neurosciences·E G Jones
Dec 14, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Damien GervasoniMiguel A L Nicolelis
Apr 6, 2006·Quality & Safety in Health Care·S NuñezA Aguirre-Jaime
Aug 2, 2007·Anesthesiology·Gerhard Schneider, Eberhard F Kochs
Oct 15, 2008·British Journal of Anaesthesia·E OlofsenA Dahan
Nov 8, 2008·Science·Michael T AlkireGiulio Tononi

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Citations

Dec 15, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shinung ChingNancy J Kopell
Dec 4, 2010·Neuroscience and Biobehavioral Reviews·David Borsook, Lino Becerra
May 28, 2011·The European Journal of Neuroscience·Helder Cardoso-CruzVasco Galhardo
Dec 31, 2014·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·José M AmigóValentina A Unakafova
Apr 21, 2012·Laboratory Animals·Aura Silva, Luis Antunes
Nov 4, 2015·International Journal of Molecular Sciences·Ruoxian DengXiaofeng Jia
Sep 18, 2013·The Open Biomedical Engineering Journal·Li ShiHong Wan
Jul 21, 2017·Frontiers in Neural Circuits·Jennifer A GuideraKen Solt
Dec 9, 2020·Entropy·Soheil Keshmiri

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