Comparison of artificial neural network and logistic regression models for predicting in-hospital mortality after primary liver cancer surgery.

PloS One
Hon-Yi ShiChong-Chi Chiu

Abstract

Since most published articles comparing the performance of artificial neural network (ANN) models and logistic regression (LR) models for predicting hepatocellular carcinoma (HCC) outcomes used only a single dataset, the essential issue of internal validity (reproducibility) of the models has not been addressed. The study purposes to validate the use of ANN model for predicting in-hospital mortality in HCC surgery patients in Taiwan and to compare the predictive accuracy of ANN with that of LR model. Patients who underwent a HCC surgery during the period from 1998 to 2009 were included in the study. This study retrospectively compared 1,000 pairs of LR and ANN models based on initial clinical data for 22,926 HCC surgery patients. For each pair of ANN and LR models, the area under the receiver operating characteristic (AUROC) curves, Hosmer-Lemeshow (H-L) statistics and accuracy rate were calculated and compared using paired T-tests. A global sensitivity analysis was also performed to assess the relative significance of input parameters in the system model and the relative importance of variables. Compared to the LR models, the ANN models had a better accuracy rate in 97.28% of cases, a better H-L statistic in 41.18% of cases, a...Continue Reading

References

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Citations

Dec 18, 2013·International Journal of Colorectal Disease·Katie Adams, Savvas Papagrigoriadis
Jul 16, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Yuan-Ting HuangHon-Yi Shi
Apr 16, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Chih-Cheng LuHon-Yi Shi
Oct 2, 2015·Journal of Biomedical Informatics·Miriam Seoane SantosArmando Carvalho
Oct 27, 2015·Indian Journal of Occupational and Environmental Medicine·Maryam FarhadianEbrahim Darvishi
Aug 21, 2015·Future Oncology·Ashley D StatonChristopher R Flowers
May 3, 2014·Seminars in Oncology·Petr Pancoska, Brian I Carr
Jun 7, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·C-C ChiuH-Y Shi
Nov 29, 2017·Healthcare Informatics Research·Leili TapakJalal Poorolajal
Jan 23, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·D BingQ Wang
Jan 27, 2015·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·K SøreideJ A Søreide
Aug 11, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hon-Yi ShiChong-Chi Chiu
Jan 17, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Aline Mähringer-KunzRoman Kloeckner
Aug 2, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Javad FaradmalAmir Kasaeian
Aug 5, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Marta Priscila Bento FernandesBalachundhar Subramaniam
Oct 23, 2020·World Journal of Gastroenterology : WJG·Miguel Jiménez Pérez, Rocío González Grande
Dec 4, 2020·World Journal of Gastroenterology : WJG·Quirino LaiMassimo Rossi

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