May 27, 1972

Comparison of aspirin and benorylate in the treatment of rheumatoid arthritis

British Medical Journal
D L BealesR Grahame


In a double-blind between-patient study of aspirin and benorylate carried out in 72 outpatients with rheumatoid arthritis, benorylate 4 g twice daily was shown to be an effective analgesic and anti-inflammatory drug, its effects being indistinguishable from those of aspirin 1.2 g four times daily. Compared with the pretreatment values both drugs produced a statistically significant improvement (P < 0.01) in functional grade, overall pain, articular index, and grip strength at the end of the first and second weeks. The overall incidence of side effects was less with benorylate, though this difference was not significant at the 5% level.

  • References5
  • Citations11
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Mentioned in this Paper

Anti-Inflammatory Agents
Aniline Compounds
Rheumatoid Arthritis
Analgesic brand of acetaminophen-phenyltoloxamine
Physical Examinations and Diagnoses

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