Comparison of Autoimmune Thyroid Disease in Patients With Progressive and Stable Vitiligo

Journal of Cutaneous Medicine and Surgery
Mohammad Javad YazdanpanahNaghmeh Zabolinejad

Abstract

Activity of vitiligo has not been considered as a patient selection criteria in previous studies; we decided to compare the presence of elevated thyroid auto-antibodies in patients with progressive and stable vitiligo. Seventy-two patients with vitiligo were examined for thyroid problems and were divided into 2 groups of stable and progressive vitiligo according to their history and physical examination. Anti-thyroid peroxidase antibodies (anti-TPO antibodies), thyroxine (T4), and thyroid stimulating hormone (TSH) levels were assessed for all patients. Elevated levels of anti-TPO antibodies were observed in 43.7% of the patients with stable vitiligo and in 37.5% of patients with progressive vitiligo, which was not statistically significant (P = .315). This study not only confirmed thyroid dysfunction in patients with vitiligo but also showed that there was no difference in thyroid dysfunction and anti-TPO antibody levels in the subgroups of patients with stable or progressive vitiligo.

References

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Citations

May 29, 2018·International Journal of Dermatology·Aisha M Dahir, Simon F Thomsen
Jan 31, 2019·Frontiers in Endocrinology·Jinping YuanHong-Duo Chen
Dec 22, 2020·Terapevticheskiĭ arkhiv·E A TroshinaN V Frigo

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Methods Mentioned

BETA
ELISA

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SPSS

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