Comparison of Automated Titanium Fasteners to Hand-Tied Knots in Open Aortic Valve Replacement

Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery
Candice Y LeePeter A Knight

Abstract

Aortic cross-clamp and cardiopulmonary bypass times are independent predictors of postoperative morbidity and mortality. Reducing ischemic times with automated titanium fasteners may improve surgical outcomes. This study compared operative times and costs of titanium fasteners versus hand-tied knots for prosthesis securement in open aortic valve replacement. A randomized control trial was conducted during a 16-month period at a single university medical center. Patients undergoing elective aortic valve replacement were randomized to the titanium fastener (n = 37) or hand-tied groups (n = 36). Knotting, aortic cross-clamp, cardiopulmonary bypass, and total operating room times were recorded. Hospital charges were also calculated for these procedures. Baseline characteristics, concomitant procedures, prosthetic valve size, and sutures were similar between groups. The titanium fastener group had significantly reduced knotting (7.4 vs. 13.0 minutes, P < 0.001), aortic cross-clamp (69 vs. 90 minutes, P < 0.05), cardiopulmonary bypass (86 vs. 114 minutes, P < 0.05), and total operating room times (234 vs. 266 minutes, P < 0.05). Intraoperative complications occurred more frequently in the hand-tied group compared with the titanium fa...Continue Reading

References

Feb 23, 2008·The Annals of Thoracic Surgery·Bari MurtuzaThanos Athanasiou
Jun 5, 2010·Journal of Clinical Anesthesia·Alex Macario
Aug 25, 2010·The Annals of Thoracic Surgery·Tirone E DavidManjula Maganti
Apr 9, 2011·The Journal of Thoracic and Cardiovascular Surgery·Willem FlamengBart Meuris
May 3, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Branko N HuisaThomas M Hemmen
Apr 12, 2014·Interactive Cardiovascular and Thoracic Surgery·John ChalmersMichael Poullis
Apr 24, 2014·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Candice Y LeePeter A Knight
May 7, 2014·Journal of Cardiovascular Translational Research·Nicolas H Pope, Gorav Ailawadi
Feb 11, 2015·The Annals of Thoracic Surgery·Douglas R JohnstonEugene H Blackstone
Aug 26, 2016·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Candice Y LeePeter A Knight
Sep 23, 2016·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·J Alan WolfeScott M Goldman

❮ Previous
Next ❯

Citations

Nov 6, 2018·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Carl A JohnsonIgor Gosev
Nov 15, 2019·Journal of Cardiac Surgery·M Yousuf SalmasiThanos Athanasiou
Oct 29, 2020·Journal of Cardiac Surgery·Ifan JenkinAmer Harky
Dec 12, 2020·The Journal of Cardiovascular Surgery·Djamila AbjigitovaAd J Bogers
Jun 17, 2021·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Ashlynn LerTheo Kofidis
Dec 11, 2020·The Annals of Thoracic Surgery·Faizus SazzadTheo Kofidis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.