Comparison of baseline characteristics, clinical features, angiographic results, and early outcomes in men vs women with acute myocardial infarction undergoing primary coronary intervention

Chest
Cheng-I ChengHon-Kan Yip

Abstract

Women have had a higher early mortality rate than men after acute myocardial infarction (AMI) in the prethrombolytic and thrombolytic eras. Primary percutaneous coronary intervention (PCI) has been shown to significantly improve survival of patients with AMI, and to be superior to thrombolytic therapy in terms of immediate restoration of normal flow in the infarct-related artery and reduction of recurrent ischemic events. However, the effect of primary PCI on early outcomes of women vs men remains unknown. Therefore, we examined whether there was any difference in term of 30-day mortality between women and men after primary PCI. Between May 1993 and April 2002, primary PCI was performed in 1,032 consecutive patients (15.3% women and 84.7% men) with AMI. The overall successful reperfusion (final Thrombolysis in Myocardial Infarction grade 3 flow) and 30-day morality rates were 84.0% and 8.5%, respectively. The rate of successful reperfusion did not differ between women and men (84.8% vs 83.9%, p = 0.77). However, mortality at 30 days was significantly higher in women than in men (14.6% vs 7.4%, p = 0.003). In comparison with men, women were older; had significantly higher incidences of hypertension, diabetes mellitus, complete a...Continue Reading

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Citations

Jul 25, 2009·JACC. Cardiovascular Interventions·P Michael GrossmanUNKNOWN Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2)
Feb 3, 2011·Cardiology in Review·Rebecca D LevitJudith S Hochman
Dec 18, 2013·European Heart Journal. Acute Cardiovascular Care·Amber M OttenUNKNOWN Zwolle Myocardial Infarction study Group
Feb 10, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Krischan D SjauwJosé P S Henriques
Apr 27, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Hakim BenamerUNKNOWN CARDIO-ARHIF Registry Investigators
Jun 19, 2007·Acute Cardiac Care·Gulmira Kudaiberdieva, Bulent Gorenek
Nov 21, 2007·Gender Medicine·Fangfei WangXiao-Ping Yang
Jul 15, 2015·International Journal of Cardiology·Chirag BavishiJacqueline E Tamis-Holland
Feb 24, 2015·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Lorenza Michela BiavaSebastiano Marra
Oct 6, 2017·European Heart Journal. Acute Cardiovascular Care·Arvindra KrishnamurthyJohn P Greenwood
Mar 23, 2017·European Heart Journal·Amélie GabetValérie Olié
Aug 3, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Corinne S BabiolakisWael Abuzeid

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