Comparison of bi- and multiparametric magnetic resonance imaging to select men for active surveillance

Acta Radiologica Open
Karen-Cecilie ThestrupHenrik S Thomsen

Abstract

Active surveillance of men with prostate cancer relies on accurate risk assessments because it aims to avoid or delay invasive therapies and reduce overtreatment. To compare the diagnostic performance of pre-biopsy biparametric magnetic resonance imaging (MRI) with confirmatory multiparametric MRI in selecting men for active surveillance. The study population included biopsy-naïve men with clinical suspicion of prostate cancer undergoing biparametric MRI followed by combined (standard plus MRI targeted) biopsies. Men diagnosed with prostate cancer who were subsequently enrolled in active surveillance and underwent a confirmatory multiparametric MRI within three months of diagnosis were included in the study. Discrepancies between the pre-biopsy biparametric MRI and the confirmatory multiparametric MRI were assessed. Overall, 101 men (median age = 64 years; median prostate-specific-antigen level = 6.3 ng/mL) were included. Nine patients were re-biopsied after multiparametric MRI for the following reasons: suspicion of targeting error (three patients); a new suspicious lesion detected by multiparametric MRI (five patients); and an increase in tumor volume (one patient) compared with biparametric MRI. Confirmatory biopsies showed ...Continue Reading

References

Aug 13, 2005·The American Journal of Surgical Pathology·Jonathan I EpsteinUNKNOWN ISUP Grading Committee
Sep 20, 2011·Korean journal of urology·Myung Sun ChoiSae Woong Kim
Nov 15, 2011·BJU International·H Ballentine Carter
Apr 1, 2012·International Journal of Endocrinology and Metabolism·Asghar Ghasemi, Saleh Zahediasl
Mar 13, 2014·Journal of Surgical Oncology·Frederik B ThomsenPeter Iversen
Sep 2, 2016·Acta Radiologica Open·Karen Cecilie Duus ThestrupHenrik S Thomsen

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