Comparison of biochemical data, blood pressure and physical activity between longevity and non-longevity districts in Japan

Circulation Journal : Official Journal of the Japanese Circulation Society
Ichiro MoriKenji Matsubara

Abstract

There is controversy about longevity-associated factors, including environmental and genetic factors. Clinical and epidemiological studies suggest that multiple risk factors decrease life-span, but there has not been a definitive report regarding the association of risk factors with longevity. The ultimate aim of the present study was to prevent the overwhelming increase in life-style-related diseases by evaluating this association in 2 districts in Japan. Plasma glucose levels, hemoglobin (Hb) A1c, lipids, dehydroepiandrosterone-sulfate, adiponectin and physical activity were examined in 133 subjects (M/F 47/86, 67+/-1 years) in Kokufu, a longevity district (mean life span: 80.4 years according to 2000 Japanese census) and 69 subjects (M/F 29/40, 62+/-1 years) in Miyama, a non-longevity district (mean life span 77.4 years, 2000 census). There were significant differences in systolic and diastolic blood pressures (BPs, p < 0.001), exercise capacity (p < 0.0001) and plasma adiponectin levels (p < 0.04) between the districts. Plasma adiponectin level was significantly correlated with high-density lipoprotein-cholesterol (HDL-C) (r = 0.333, p < 0.0001), triglyceride (TG) (r = -0.161, p < 0.04), HbA1c (r = -0.163, p < 0.03) and HOM...Continue Reading

References

May 1, 1977·Lipids·T T YenM M Greenberg
Feb 1, 1991·Journal of the American Geriatrics Society·D Podsiadlo, S Richardson
Sep 23, 1971·The New England Journal of Medicine·J C Melby
Nov 17, 1998·Journal of Clinical Epidemiology·S FukuharaK Kurokawa
Nov 17, 1998·Journal of Clinical Epidemiology·S FukuharaB Gandek
Jan 14, 1999·The American Journal of Physiology·T IshizukaK Yasuda
Mar 27, 1999·Biochemical and Biophysical Research Communications·Y AritaY Matsuzawa
Aug 6, 2002·Science·George S RothE Jeffrey Metter
Jan 28, 2003·Lancet·Joachim SprangerAndreas F H Pfeiffer
Jun 19, 2007·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·Hiroyuki Hashidate, Yasushi Uchiyama
Oct 30, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Fumiyuki OtsukaHisao Ogawa
Dec 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Noriyuki KomuraUNKNOWN Osaka CAD Group

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Citations

Feb 9, 2010·Antioxidants & Redox Signaling·Carlotta GiorgiPaolo Pinton
Aug 8, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Yuan-Chi LeeMing-Fong Chen
Feb 11, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Mamoru Nanasato, Toyoaki Murohara
Sep 15, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Hisashi Adachi
Feb 15, 2012·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Carla J BergJasjit S Ahluwalia
Aug 5, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Hidetoshi KashiharaAkira Akabayashi
Mar 6, 2010·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Omar F KhabourKarem H Alzoubi

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