Comparison of breath-hold and free-breathing positions of an external fiducial by analysis of respiratory traces.

Journal of Applied Clinical Medical Physics
Sandeep HunjanPeter Balter

Abstract

An internal target volume (ITV) accounting for respiratory-induced tumor motion is best obtained using 4DCT. However, when 4DCT is not available, inspiratory/expiratory breath-hold (BH insp, BH exp) CT images have been suggested as an alternative. In such cases, an external fiducial on the abdomen can be used as a substitute for tumor motion and CT images are acquired when the marker position matches - as judged by the therapist/physicist - its positions at previously determined free-breathing (FB) respiratory extrema (FB insp, FB exp). In this study we retrospectively determined the accuracy of these matches. Free breathing 4DCT images were acquired, followed by BH insp and BH exp CT images for 25 patients with non-small-cell lung cancer. Respiration was monitored using a commercial external fiducial system, which generates positional information while CT studies are conducted. Software was written for statistically analyzing the displacement of the external fiducial during BH insp and BH exp CT acquisition and comparing these displacements with corresponding mean FB extrema positions (FB insp and FB exp, respectively) using a Student's t-test. In 72% of patients, mean positions at BH insp differed significantly from mean posi...Continue Reading

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Citations

Feb 6, 2010·International Journal of Radiation Oncology, Biology, Physics·Sandeep HunjanPeter Balter
Mar 17, 2017·Journal of Applied Clinical Medical Physics·Evangelia KazaMartin O Leach

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4DCT
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