Comparison of bupivacaine and lidocaine/bupivacaine for local anesthesia/digital nerve block

Annals of Emergency Medicine
M N Valvano, S Leffler

Abstract

We compared the efficacy, degree of discomfort, and time elapsed before anesthesia of digital block with a combination of 1% lidocaine/.25% bupivacaine and with .25% bupivacaine alone. We carried out a randomized, double-blinded, prospective study in which subjects served as their own controls. The study group comprised 19 normal adult volunteer medical students and members of the community who volunteered to participate in a study evaluating "the use of commonly used local anesthetics by physicians." Two digital blocks were performed on each subject: one with a lidocaine/bupivacaine combination and one with bupivacaine alone. Two subjects did not complete the study; therefore 34 blocks were performed. Both the physicians and subjects were blinded to the anesthetic used for each block. Patients immediately rated the pain associated with each technique on a standard visual analog scale. Time elapsed before onset of anesthesia to pinprick was assessed and recorded after each block in 1-minute increments. We assessed efficacy on the basis of anesthesia to pinprick. Mean visual analog scale pain scores were not different between the two types of blocks: 3 cm for lidocaine/bupivacaine and for bupivacaine alone (P = .76, Student t te...Continue Reading

Citations

Jan 1, 1997·The Journal of Emergency Medicine·C L RosenP T Pons
Apr 23, 2002·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·David Julian Seager, Cam Simmons
Jul 1, 2008·Neuromodulation : Journal of the International Neuromodulation Society·Elliot S KramesRichard L Weiner
Mar 14, 2007·Emergency Medicine Journal : EMJ·Jia Jia ShenCatherine E MacBean
Jan 6, 2009·The Journal of Hand Surgery·Neil G Harness
Jul 29, 2006·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Erdal EroğluBaydar Metin Lütfi
Feb 14, 2015·Veterinary Ophthalmology·Derek W Y ChowHans D Westermeyer
Apr 19, 2012·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Paul M SimpsonPaul M Middleton
Mar 13, 2014·The Journal of Hand Surgery·Toby I Vinycomb, Lukas J Sahhar
Mar 21, 2007·British Journal of Hospital Medicine·Sertaz-Niel Kang
Jan 17, 2014·The Canadian Journal of Plastic Surgery = Journal Canadien De Chirurgie Plastique·James B CollinsRaman C Mahabir
Jan 19, 2021·European Journal of Plastic Surgery·Edward Paul Joseph MuscatJuan Enrique Berner

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