Abstract
Prospective, cohort, non-inferiority study. This study evaluated the clinical and radiological outcomes of interbody fusion using a combination of demineralized bone matrix (DBM) and hydroxyapatite (HA). The use of autografts remains a gold standard in lumbar interbody fusion, but the limited availability and donor site morbidity encourages the use of bone substitutes. In addition to autografts, a combination of HA and DBM is being increasingly use for lumbar interbody fusion. However, there are no data on the clinical and radiological outcomes of this procedure. We examined 35 patients with lumbar degenerative spondylolisthesis who underwent transforaminal interbody fusion. Autografts were used in 18 patients, and 17 patients received a combination of HA and DBM. Clinical outcomes were evaluated using the visual analog scale (VAS) for back and leg pain, Oswestry disability index (ODI), and Japanese Orthopaedic Association (JOA) scores at 3, 6, and 12 months postoperatively. Fusion was evaluated using computed tomography images obtained at 12 months postoperatively. The mean ODI, JOA, and back and leg pain VAS scores increased significantly in both groups. However, the VAS, JOA, and ODI scores did not differ significantly betwe...Continue Reading
References
Oct 1, 1994·Spine·D G Little, D MacDonald
Nov 5, 1997·Spine·C L SchneeP J Marcotte
Aug 4, 2001·Neurosurgical Review·K IdoS Kuriyama
Jan 24, 2002·Spine·Tomoyuki HashimotoShigeru Yamane
Oct 16, 2003·Spine·Yasushi MiuraHiroaki Kachi
Apr 27, 2005·The Journal of the American Academy of Orthopaedic Surgeons·Safdar N KhanJoseph M Lane
Mar 28, 2006·International Orthopaedics·Ali OztürkHalil Can Gemalmaz
May 10, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Travis HuntVincent Arlet
Oct 11, 2008·Clinical Orthopaedics and Related Research·Ching-Hsiao YuPo-Quang Chen
Jan 20, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Anthony M T Chau, Ralph J Mobbs
Mar 13, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Masashi MiyazakiAhmet Alanay
May 27, 2009·Current Reviews in Musculoskeletal Medicine·Chad D ColeAndrew T Dailey
Jan 6, 2011·Biomedical Materials·Jae Hyup LeeHyun-Seung Ryu
Nov 29, 2011·World Neurosurgery·Manish K Kasliwal, Harel Deutsch
Mar 28, 2012·Türkiye parazitolojii dergisi·Duygu Neval Sayın Ipek, Polat Ipek
Dec 19, 2012·Organogenesis·Timothy T Roberts, Andrew J Rosenbaum
Jan 3, 2013·The Journal of the American Academy of Orthopaedic Surgeons·Gregory Grabowski, Chris A Cornett
Mar 22, 2014·World Journal of Orthopedics·Konstantinos TilkeridisGeorgios I Drosos
Jun 1, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Hui HuangXiaoxing Jiang
Aug 19, 2014·Journal of Korean Neurosurgical Society·Young Seok LeeYoung Baeg Kim
Jan 13, 2015·International Journal of Spine Surgery·Gerard GirasoleJason Chertoff
Jan 30, 2015·Journal of Korean Neurosurgical Society·Young Seok LeeChan Chung
Jan 1, 2013·International Journal of Spine Surgery·Jack E Zigler, Rick B Delamarter
Nov 21, 2015·Journal of Korean Neurosurgical Society·Kyoung-Min JangYoung-Seok Lee