Comparison of clinical characteristics and outcomes of patients with COPD exacerbation with or without venous thromboembolism

Respiration; International Review of Thoracic Diseases
Metin AkgunArzu Mirici

Abstract

Although some studies evaluated venous thromboembolism (VTE) prevalence in patients with chronic obstructive pulmonary disease (COPD), they contain no detailed description of the patients' characteristics. It was the aim of this study to investigate the frequency and clinical characteristics and outcomes of VTE in patients with COPD exacerbation. Between October 2004 and February 2005, 120 consecutive patients were included in the study. On admission, Doppler examination of lower extremities in all cases and spiral computed tomography of the thorax in cases with a suspicion of pulmonary thromboembolism were performed. A questionnaire was used to take a detailed history. In addition to routine laboratory tests, chest X-ray, postbronchodilator spirometry, arterial blood gas analysis and serum levels of D-dimer and C-reactive protein were evaluated, as well as dyspnea score and performance status before exacerbation. The hospitalization durations and mechanical ventilation requirements were also recorded. VTE was determined in 16 cases (13.3%). In patients with VTE, the travel history was higher (p < 0.001), the dyspnea score worse (p = 0.005), the duration of hospitalization longer (p < 0.001) and the mechanical ventilation requi...Continue Reading

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Citations

May 23, 2012·COPD·Denise Rossato SilvaMarli Maria Knorst
Sep 19, 2014·The American Journal of the Medical Sciences·Oren FruchterMordechai R Kramer
Oct 29, 2008·The American Journal of Medicine·Raza Alikhan, Alex C Spyropoulos
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Feb 2, 2016·The European Respiratory Journal·Mareike Lankeit, Matthias Held
Aug 14, 2012·The American Journal of Medicine·Gregory PiazzaFrederick A Spencer

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