Abstract
A substantial proportion of adolescent schizophrenia patients exhibit obsessive-compulsive symptoms/disorder (OCS/OCD). In the present study we sought to provide a clinical characterization of adolescent schizo-obsessive patients. A consecutive sample of 22 adolescent patients (age 13-18 years) who met DSM-IV criteria for both schizophrenia and OCD was compared with 22 non-OCD schizophrenia patients matched for age, gender and number of hospitalizations. The Structured Clinical Interview for DSM-IV Axis I psychiatric disorders (SCID-I), the Scale for the Assessment of Positive (SAPS) and Negative (SANS) Symptoms, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and the Clinical Global Impression (CGI) were used. We found that schizo-obsessive patients had earlier age at onset of schizophrenia symptoms, had more OCD spectrum disorders, primarily tic disorders, but did not differ in severity of schizophrenia symptoms from non-OCD schizophrenia patients. In a majority of the schizo-obsessive patients, OCS preceded or co-occurred with the onset of schizophrenia and did not correlate with schizophrenic symptoms. As expected, more schizo-obsessive patients than their non-OCD counterparts were treated with adjunctive anti-obsessive ...Continue Reading
References
Nov 1, 1989·Archives of General Psychiatry·W K GoodmanD S Charney
Apr 1, 1986·The American Journal of Psychiatry·W S Fenton, T H McGlashan
May 3, 1997·Schizophrenia Research·I BermanA I Green
Apr 1, 1998·The Journal of Nervous and Mental Disease·I BermanA I Green
Mar 1, 2000·The Journal of Nervous and Mental Disease·P H LysakerG R Bond
Mar 17, 2000·Brain Research. Brain Research Reviews·R NicolsonJ L Rapoport
Apr 12, 2000·Journal of Psychiatric Research·P TibboL Warneke
Sep 30, 2000·Comprehensive Psychiatry·C SobinM Karayiorgou
May 23, 2001·Psychiatry Research·M PoyurovskyA Weizman
Jan 10, 2003·Psychiatry and Clinical Neurosciences·Masayuki OhtaYoshio Morita
Apr 10, 2003·The Psychiatric Clinics of North America·Alan I GreenJoanne D Wojcik
May 3, 2003·The American Journal of Psychiatry·Allon NechmadRonit Weizman
Mar 10, 2004·Psychiatry Research·Paul H LysakerLouanne W Davis
Oct 19, 2004·Journal of Affective Disorders·Jitender SareenJeffrey P Reiss
Dec 9, 2004·CNS Drugs·Michael PoyurovskyRonit Weizman
Jan 7, 2005·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Michael PoyurovskyRonit Weizman
May 12, 2005·Schizophrenia Research·Dost Ongür, Donald C Goff
Jun 14, 2005·Schizophrenia Research·Matthew ByerlyA John Rush
Jun 28, 2006·Molecular Psychiatry·A Jablensky
Oct 31, 2006·Psychiatry Research·Levent SevincokHülya Arslantas
Citations
May 6, 2014·Comprehensive Psychiatry·Alvaro FríasInma Bernáldez
Sep 27, 2014·Current Psychiatry Reports·Trehani M FonsekaDaniel J Müller
Nov 18, 2008·Schizophrenia Bulletin·Peter F BuckleyDavid J Castle
Apr 3, 2009·The Journal of Clinical Investigation·Simran K Kalra, Susan E Swedo
Nov 27, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Naomi A FinebergEric Hollander
Jun 1, 2013·BMC Psychiatry·Kristen HagenTor Ketil Larsen
Apr 12, 2013·Psychological Medicine·M SubramaniamS A Chong
Sep 10, 2013·Child and Adolescent Psychiatric Clinics of North America·Linmarie Sikich
Sep 8, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Alp ÜçokRaşit Tükel
Jun 23, 2011·Neuroscience and Biobehavioral Reviews·Judith R Homberg
Oct 14, 2014·Comprehensive Psychiatry·Sugnyani DeviY C Janardhan Reddy
Oct 1, 2016·Psychiatry Research·Diane Grillault Laroche, Adeline Gaillard
Dec 19, 2016·European Archives of Psychiatry and Clinical Neuroscience·Frederike SchirmbeckUNKNOWN GROUP investigators
Jun 1, 2013·The Australian and New Zealand Journal of Psychiatry·Nienke DekkerUNKNOWN GROUP Investigators
Oct 5, 2017·Clinical Neuropharmacology·Burak BaytuncaDost Öngur
Jul 22, 2018·Korean journal of family medicine·Eun-Ji LeeSeo-Rim Hong
Jul 3, 2019·Current Psychiatry Reports·Chloé Tezenas du MontcelBaptiste Pignon
Jan 8, 2015·Harvard Review of Psychiatry·Luigi AttademoRoberto Quartesan
Oct 21, 2015·CNS Drugs·Henk Temmingh, Dan J Stein
Feb 1, 2020·Indian Journal of Psychiatry·Ahmet Kokurcan, Şerif Bora Nazlı
Mar 11, 2017·Psychopharmacology·A MerchánP Flores
Mar 11, 2020·Asian Journal of Psychiatry·Ji Hyun BaekKyung Sue Hong
Feb 13, 2017·Psychiatry Research·Sandeep GroverAjit Avasthi