Comparison of Clinical Characteristics of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Young Children

Japanese Journal of Infectious Diseases
Akinobu TaniguchiNagoya Collaborative Clinical Research Team

Abstract

Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are the leading causes of acute respiratory tract infection in children, and clinical manifestations of these virus infections are considered similar. To investigate the differences in clinical characteristics between HMPV and RSV infections in young children, we prospectively enrolled children < 3 years old who required hospitalization with acute respiratory tract infection due to HMPV or RSV at 10 hospitals in Japan. We enrolled 48 children with HMPV infection and 141 with RSV infection. Patients with HMPV infection were older than those with RSV infection. High-grade fever was more frequently observed in patients with HMPV infection, whereas no significant differences in respiratory symptoms were apparent. Abnormal serum lactate dehydrogenase values and consolidation shadows on chest X-ray were more frequently observed in patients with HMPV infection. During hospitalization, nasal mucus suction was more frequently required in patients with RSV infection. On the other hand, β2-adrenergic agonists, corticosteroids, and leukotriene receptor antagonists were more frequently used in patients with HMPV infection. These findings suggest that HMPV and RSV infections ...Continue Reading

References

Aug 1, 1996·The European Respiratory Journal·M DrentM van Dieijen-Visser
Jun 5, 2003·Emerging Infectious Diseases·Guy BoivinPierre Déry
Jul 23, 2003·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Miwako SaikusaChiharu Kawakami
Jan 30, 2004·The New England Journal of Medicine·John V WilliamsJames E Crowe
Jul 22, 2004·The Cochrane Database of Systematic Reviews·H PatelE E L Wang
Nov 11, 2010·Clinical Chemistry and Laboratory Medicine : CCLM·Kiyoshi IchiharaUNKNOWN IFCC Committee on Reference Intervals and Decision Limits (C-RIDL)
Dec 4, 2013·Pediatrics in Review·Jennifer E Schuster, John V Williams
May 21, 2014·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Swagatika PandaSubrat Kumar
Jun 18, 2014·The Cochrane Database of Systematic Reviews·Anne M Gadomski, Melissa B Scribani
Oct 16, 2014·Deutsches Ärzteblatt International·Jens Christian KrausePhilipp Henneke
Mar 17, 2015·The Cochrane Database of Systematic Reviews·Fang LiuRufu Xu

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Citations

May 14, 2019·Saudi Journal of Medicine & Medical Sciences·Ali Mohammed AlsuheelSaleh Mohammed Al-Qahtani
May 18, 2021·Frontiers in Pediatrics·Zhi LiuDongchi Zhao

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