Comparison of clinical history and dermatologic findings in 29 dogs with severe eosinophilic dermatitis: a retrospective analysis

Veterinary Dermatology
Elizabeth A MauldinD O Morris

Abstract

The medical records and histopathological sections of 29 dogs diagnosed with a unique eosinophilic dermatitis resembling Wells' syndrome were reviewed in an attempt to elucidate the pathogenesis of this syndrome. The medical records were reviewed for information on dermatological lesion appearance, systemic signs in other organ systems, clinical analyte abnormalities, and drug therapy. Histological sections of dogs with moderate to severe eosinophilic dermatitis without folliculitis and furunculosis were reviewed and evaluated for the presence of collagen flame figures. Three categories of patients were found. Category 1 consisted of 17 dogs treated for vomiting and/or diarrhoea (often haematochezia or haematemesis) prior (mean: 4.6 days) to the onset of skin lesions. Fourteen category 1 dogs had erythematous lesions (macules, papules or plaques) that were most pronounced on the abdomen. Sixteen of the 17 dogs received multiple classes of drugs, and 59% were hypoalbuminemic. Category 2 consisted of five dogs that had skin lesions and gastrointestinal signs at presentation and four of these dogs were hypoalbuminemic. Category 3 included seven dogs without enteric illness. A positive drug score was found in six category 1 dogs an...Continue Reading

References

Jan 1, 1979·The British Journal of Dermatology·G C Wells, N P Smith
Sep 1, 1988·Clinical and Experimental Dermatology·J A Newton, M W Greaves
Jan 1, 1988·Journal of the American Academy of Dermatology·W AbererK Wolff
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Jul 1, 1983·Clinical and Experimental Dermatology·H M van den Hoogenband
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Aug 22, 2000·The British Journal of Dermatology·D CanonneE Delaporte
May 1, 2001·International Journal of Dermatology·M MariniG Magariños
May 1, 2001·International Journal of Dermatology·G WeissH Trau
Feb 13, 2003·International Journal of Dermatology·Meena Moossavi, Darius R Mehregan
Jul 10, 2004·Immunology and Allergy Clinics of North America·Jeffrey K McKenna, Kristin M Leiferman
Oct 30, 2004·Current Opinion in Immunology·Basil O Gerber, Werner J Pichler

Citations

Apr 24, 2012·Journal of Veterinary Internal Medicine·K L VoieS N Lavergne
Feb 9, 2010·The Journal of Small Animal Practice·C ElwoodK Savary-Bataille
Dec 1, 2017·Journal of the American Veterinary Medical Association·Christine L CainElizabeth A Mauldin
Apr 21, 2020·Veterinary Dermatology·Carolyn B EmeryStephen D White

Related Concepts

Dermatitis
Dog Diseases
Canis familiaris
Eosinophilia, Tropical
Retrospective Studies

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