PMID: 11903749Mar 21, 2002Paper

Comparison of clinicopathological features of patients with hepatocellular carcinoma seropositive for alpha-fetoprotein alone and those seropositive for des-gamma-carboxy prothrombin alone

Journal of Gastroenterology and Hepatology
H OkudaM Nakano

Abstract

There has been no comparative study of the clinicopathological features of HCC patients who are seropositive for alpha-fetoprotein (AFP) alone and those who are seropositive for des-gamma-carboxy prothrombin (DCP) alone. The authors, thus, performed this comparative study. The clinicopathological features of patients with solitary hepatocellular carcinoma (HCC), who underwent a hepatectomy were compared among the four below groups according to the seropositivity of AFP and DCP: group A, seronegative for both AFP below 20 ng/mL and DCP below 40 mAU/mL; group B, seropositive for AFP above 100 ng/mL and seronegative for DCP; group C, seronegative for AFP and seropositive for DCP above 100 mAU/mL; and group D, seropositive for both AFP and DCP. Group B patients showed a higher incidence of HCC with an indistinct margin, and a somewhat higher incidence of small HCC less than 2 cm in greatest dimension compared with group C patients. By contrast, group C patients had a higher frequency of HCC with a distinct margin compared with that of an indistinct margin, large tumors more than 3 cm compared with that of small tumors less than 2 cm, and a somewhat higher frequency of moderately to poorly differentiated HCC compared with that of we...Continue Reading

References

Jul 1, 1991·Journal of Gastroenterology and Hepatology·H OkudaH Obata
Jul 1, 1986·Seminars in Thrombosis and Hemostasis·D H CarneyJ W Fenton
May 31, 1984·The New England Journal of Medicine·H A LiebmanB Furie

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Citations

Feb 1, 2008·Annals of Surgical Oncology·Roberta W C PangRonnie T P Poon
Sep 7, 2013·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Naota TauraKazuhiko Nakao
Mar 25, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Tomomi Masuda, Eiji Miyoshi
Nov 20, 2012·Hepatitis Monthly·Mona Abu El Makarem
Aug 1, 2007·Biomarkers in Medicine·Nikki P Y LeeJohn M Luk
Nov 4, 2011·Journal of Gastroenterology·Hideaki KinugasaKazuhide Yamamoto
Aug 17, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Yoichi YanoMichio Sata
Dec 2, 2017·Nigerian Journal of Clinical Practice·Akpakip Ikpong EtteU Ekrikpo
Sep 7, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hideki YokooSetsuo Hirohashi
Apr 13, 2012·European Journal of Gastroenterology & Hepatology·Se Hun KangKwang-Hyub Han
Mar 15, 2006·World Journal of Gastroenterology : WJG·Lin ZhouFeng Luo
Feb 2, 2019·World Journal of Hepatology·Maria J CitoresValentin Cuervas-Mons
Jun 10, 2008·Clinica Chimica Acta; International Journal of Clinical Chemistry·Evi N Debruyne, Joris R Delanghe
Oct 14, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Richard K SterlingMorris Sherman
Jun 18, 2011·Critical Reviews in Oncology/hematology·Ashish SinghalVivek Kohli

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