Comparison of collagen gene sequences in Ascaris suum and Caenorhabditis elegans.

Molecular and Biochemical Parasitology
I B KingstonD Cooper

Abstract

The nucleotide sequences of a 3060-bp fragment containing almost the entire coding sequence of one Ascaris suum collagen gene, and a 3019-bp pair fragment containing the 3' end of another A. suum collagen gene have been determined. The polypeptides encoded by these genes show a striking similarity to two Caenorhabditis elegans cuticular collagens, both in the position of the triple-helical regions and in the position of cysteine residues. The results of Northern blot hybridisation experiments together with dot blot analysis of RNA isolated from different adult worm tissues suggest that one of these genes is expressed in the adult nematode and that it encodes a protein of approximately 30 kDa.

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Citations

Mar 1, 1994·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·I L Johnstone
Sep 1, 1996·Molecular and Biochemical Parasitology·I L JohnstoneJ D Barry
Jan 1, 1991·Parasitology Today·I B Kingston
Sep 1, 1992·Parasitology Today·M P Hammond, A E Bianco
Jan 1, 1992·Parasitology Today·S M Politz, M Philipp
Dec 2, 1996·Molecular and Biochemical Parasitology·C RayR S Hussey
Nov 1, 2001·Trends in Parasitology·S HashmiS Lustigman
Mar 6, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Melanie C TheinAntony P Page
Jul 1, 1990·Acta Tropica·B Betschart, K Wyss

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