Comparison of computed tomography and magnetic resonance imaging in cervical cancer brachytherapy target and normal tissue contouring

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Ramez N EskanderCatherine Yashar

Abstract

To evaluate the differences between target and normal tissue delineation between magnetic resonance imaging (MRI) and computed tomography (CT) in cervical cancer patients and to explore the differences in dosimetry after brachytherapy planning. High-dose-rate brachytherapy was performed on 11 patients. Planning CT and MRI were performed with tandem and ring in place. The radiation oncologist contoured the rectum, the bladder, the sigmoid, and the high-risk clinical target volume (HR-CTV) on CT and MRI. The values compared between CT and MRI included D90 and D100 to HR-CTV; coronal, sagittal, and axial measurements of HR-CTV; and minimum dose to most irradiated 0.1-, 0.5-, 1.0-, and 2.0-cm volumes for the organs at risk (OAR). Doses were converted to the equivalent dose in 2 Gy by applying the linear quadratic model. Volume optimization was also performed, and the above parameters were evaluated. Magnetic resonance imaging showed a significantly greater HR-CTV length in the sagittal plane (P = 0.006), with CT showing a greater length in the coronal plane (P = 0.004). The equivalent dose in 2 Gy to 2.0 cm for the bladder was greater on CT than MRI (P = 0.041). The remainder of the dose volume histogram values for the OAR were sim...Continue Reading

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Citations

Feb 22, 2012·Japanese Journal of Clinical Oncology·Rahul KrishnatryArvind K Shukla
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May 22, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Umesh MahantshettyNapapat Amornwichet

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