Comparison of Contrast-Enhanced Multiphase Renal Protocol CT Versus MRI for Diagnosis of Papillary Renal Cell Carcinoma

AJR. American Journal of Roentgenology
Marc DilauroNicola Schieda

Abstract

The objective of this study was to compare contrast-enhanced (CE) CT with MRI for the diagnosis of papillary renal cell carcinoma (pRCC). Between 2006 and 2013, a total of 27 pRCCs were assessed using CECT or CE-MRI. A blinded radiologist placed ROIs that measured attenuation on unenhanced CT; corticomedullary and nephrographic phase CECT images, with an attenuation difference of 20 HU or more denoting enhancing lesions, 10-19 HU indicating indeterminate findings, and less than 10 HU denoting nonenhancing lesions. MRI enhancement ratios were calculated as follows: (signal intensity on gadolinium-enhanced image minus signal intensity) / (signal intensity on unenhanced image × 100) for phase 1 (acquired at 30 s), phase 2 (acquired at 70 s), and phase 3 (acquired at 180 s), where a difference of 15% or more denoted enhancement. Two additional blinded radiologists qualitatively assessed tumor margin, homogeneity, and calcification with the use of CT, and they also assessed enhancement with the use of subtraction MRI. A fourth radiologist established consensus. Twenty consecutive hemorrhagic/proteinaceous cysts served as a control group. Statistical analyses were performed using a chi-square test and multivariate regression. There w...Continue Reading

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Citations

Oct 20, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ryan D WardErick M Remer
Feb 5, 2019·AJR. American Journal of Roentgenology·Jean-Paul SalamehNicola Schieda
Oct 2, 2019·AJR. American Journal of Roentgenology·Daniel R LudwigMotoyo Yano
May 16, 2018·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Abdulmohsen AlrashedMostafa Atri
May 27, 2020·Abdominal Radiology·Amar UdareNicola Schieda
Apr 19, 2018·The British Journal of Radiology·Zhen J WangRonald J Zagoria
Oct 4, 2020·Journal of Magnetic Resonance Imaging : JMRI·Satheesh KrishnaMatthew S Davenport
Oct 14, 2020·Abdominal Radiology·Tatsuya YamamotoKentaro Inamura
Mar 26, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Lorena ConsolinoDario Livio Longo
Apr 17, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Nicola SchiedaStuart G Silverman
Jun 1, 2021·Radiologic Clinics of North America·John J HinesRiya Goyal
May 25, 2020·Seminars in Ultrasound, CT, and MR·Satheesh KrishnaAshish Khandelwal
May 22, 2021·European Journal of Radiology·Athina C TsiliUNKNOWN Oncologic Imaging Subcommittee Working Group of the Hellenic Radiological Society
Oct 29, 2021·Acta Radiologica·Athina C TsiliMaria I Argyropoulou

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