Comparison of corneal morphological characteristics between diabetic and non diabetic population

Pakistan Journal of Medical Sciences
Qamar Ul IslamZulfiqar Ali Amin

Abstract

To compare corneal morphological parameters between diabetics and age matched non-diabetic control subjects and to evaluate the correlation of these parameters in relation to duration of diabetes mellitus (DM), glycemic status and severity of diabetic retinopathy.(DR). This cross sectional comparative study was conducted at the Department of Ophthalmology, PNS Shifa Karachi from February 2016 to January 2017. Patients with ages between 10 to 80 years of either gender who were diagnosed to have DM were recruited in the study. Control group comprised of age matched healthy volunteers who did not have DM. Corneal morphological parameters (CED, Average cell size, CV of cell size and hexagonality) was evaluated in each subject with non-contact specular microscope and findings were endorsed on a pre devised proforma. Data of 298 eyes (149 diabetic patients and 149 healthy controls) was evaluated. Mean corneal endothelial cell density (CED) of diabetic population was 2494.47 ± 394.10 cells/mm2, while mean CED of control group was 2574.46 ± 279.97 cells/mm2[p = 0.04]. Between group differences in mean average cell size, CV of cell size and hexagonality was statistically not significant. Analysis of corneal endothelial parameters among ...Continue Reading

Citations

Oct 17, 2019·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Irfan Durukan
Jun 5, 2020·BMC Ophthalmology·Nurdan Gamze TaşlıEmin Murat Akbas
Jul 6, 2019·Journal of Ophthalmology·María A Del BueyFrancisco J Ascaso
Jan 12, 2020·Survey of Ophthalmology·Andrew S GoldsteinMark A Greiner
Feb 12, 2021·BMC Ophthalmology·Kaikai ZhangMeisheng Zhao

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