Comparison of Corticosteroid Injection Dosages in Mild to Moderate Idiopathic Carpal Tunnel Syndrome: A Randomized Controlled Trial

Archives of Physical Medicine and Rehabilitation
Po-Cheng HsuJia-Chi Wang

Abstract

To evaluate whether the therapeutic effect of ultrasound-guided injections with 10 mg or 40 mg triamcinolone acetonide (TA) was dose-dependent in patients with idiopathic mild to moderate carpal tunnel syndrome (CTS). Prospective, double-blind, randomized controlled study with 12 weeks of follow-up. Rehabilitation outpatient clinic of a single medical center. Patients with CTS (N=56). Participants were randomly assigned to 2 treatment groups for injection: (A) 40 mg TA+2% lidocaine hydrochloride or (B) 10 mg TA+2% lidocaine hydrochloride. Participants were evaluated using visual analog scale (VAS) and Boston Carpal Tunnel Questionnaire (BCTQ, including Symptom Severity Scale [SSS] and Functional Status Scale [FSS]) at baseline and 6 and 12 weeks after injection). Nerve conduction studies, including parameters of distal motor latency, amplitude of compound motor action potential, amplitude of sensory nerve action potential and sensory nerve conduction velocity of median nerve, and the patient's subjective impression of improvement, were recorded before injection and 6 and 12 weeks after injection. No significant differences were observed in baseline demographic characteristics and clinical evaluations. The parameters in group A ...Continue Reading

Associated Clinical Trials

Citations

Mar 19, 2021·European Journal of Physical and Rehabilitation Medicine·Kamal MezianLevent Özçakar

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