PMID: 6977392Feb 1, 1982Paper

Comparison of currently available monoclonal antibodies with conventional markers for phenotyping of one hundred acute leukemias

Blut
E ThielS Thierfelder

Abstract

One hundred acute leukemia cell samples (89 ALL, 11 AMML) derived from children's bone marrow at diagnosis were typed for the reaction with 15 monoclonal antibodies (mAbs). Subdivision in ALL-subgroups was performed according to conventional markers. Only some mAbs like VIL-Al which is directed against the cALL-antigen, can substitute polyclonal rabbit antisera. Additional subclassifications became evident by the use of mAbs for T-cell differentiated ALL forms. However, unexpected negative reactions must be taken into account as observed for all T-directed mAbs with individual T-cell ALL samples.

References

Dec 1, 1979·The Journal of Experimental Medicine·E L ReinherzS F Schlossman
Mar 1, 1979·European Journal of Immunology·A J McMichaelC Milstein
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·E L ReinherzS F Schlossman
Jan 1, 1981·The Journal of Experimental Medicine·M KamounR C Nowinski
Mar 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·E G EnglemanR Levy

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Citations

Aug 1, 1984·European Journal of Pediatrics·G Gaedicke, H G Drexler
Jan 1, 1983·Leukemia Research·H G Drexler, G Gaedicke
Jan 1, 1985·Critical Reviews in Oncology/hematology·E Thiel
Aug 22, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Márcio SoaresNelson Spector
Feb 1, 1986·Scandinavian Journal of Haematology·G KovacsE Thiel

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