Comparison of defect size between thallium-201 and technetium-99m tetrofosmin myocardial single-photon emission computed tomography in patients with single-vessel coronary artery disease

The American Journal of Cardiology
I MatsunariK Hisada

Abstract

Defect size on exercise-rest technetium (Tc)-99m tetrofosmin myocardial perfusion imaging was compared with that on exercise-reinjection thallium-201 imaging with 20 patients with 1-vessel coronary artery disease. In each patient, exercise-reinjection thallium-201 single-photon emission computed tomography (SPECT) and exercise-rest Tc-99m tetrofosmin SPECT imaging were performed. For visual analysis of the obtained SPECT images, the left ventricular myocardium was divided into 20 segments based on 3 short-axis slices from the apical, middle, and basal ventricular levels. For quantitative analysis, a square region of interest was placed on the center of each segment which was used for visual analysis, and relative regional activity to the normal reference region was calculated for each segment. By visual interpretation of the images, exercise Tc-99m tetrofosmin imaging showed a smaller defect size than exercise thallium-201 imaging (6.9 +/- 3.9 vs 8.8 +/- 3.0 segments, p <0.01). In contrast, rest Tc-99m tetrofosmin imaging showed a defect size similar to that on reinjection thallium-201 imaging (5.9 +/- 3.6 vs 5.6 +/- 3.9 segments, p = NS). Similarly, the mean defect sizes during exercise determined by quantitative analysis were...Continue Reading

References

Aug 1, 1977·Circulation·H F WeichB Pitt

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Citations

Nov 26, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·David R OkadaRicardo C Cury
Feb 21, 2004·International Journal of Cardiology·Yasushi AkutsuTakashi Katagiri
Nov 18, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Ichiro MatsunariNorihisa Tonami
May 1, 1997·Annals of Nuclear Medicine·N TamakiJ Konishi
Oct 17, 2009·JACC. Cardiovascular Imaging·Vasken Dilsizian
Apr 17, 2001·Cardiology in Review·P Kailasnath, A J Sinusas
Jan 31, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gilles Barone-RochetteCatherine Ghezzi
Mar 20, 2008·Nuclear Medicine Communications·Vincent J B RobinsonMahendra K Mandawat
Jun 17, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Peter P SteeleJohn E Koss

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