Comparison of del Nido Cardioplegia and Blood Cardioplegia in Aortic Root Surgery.

The Heart Surgery Forum
Yusuf KuserliAli Aycan Kavala

Abstract

To compare del Nido cardioplegia (DNC) with conventional blood cardioplegia (BC) in aortic root surgery. Subjects who underwent aortic root surgery during a 3-year period were included. A DNC group was compared with a matched BC group. A total of 72 subjects were included, 36 who underwent DNC compared with 36 propensity-matched subjects who underwent BC. Fifty-one (70.8%) were male, and 21 (29.2%) were female, with a mean age of 66.19 ± 7.02 years (range 51 to 81). No significant differences in baseline characteristics, preoperative echocardiogram parameters, or intraoperative parameters were found between the groups. For DNC versus BC, cardiopulmonary bypass time, aortic clamp time, cardioplegia volume (all P = .001), and defibrillation (P = .007) were significantly lower. For postoperative biochemical parameters, creatinine levels at hour 24, potassium levels at hours 1 and 24, and glucose levels at hours 6 and 24 did not differ between the groups (P > .05). Creatine kinase-MB and troponin T levels at hours 1 and 24 were significantly lower in DNC versus BC (all P = .001). Hematocrit levels at hours 6 and 24 were significantly higher in DNC (P = .001). The groups did not differ in terms of postoperative inotropic support, po...Continue Reading

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