PMID: 11605755Oct 19, 2001Paper

Comparison of denuder and impinger sampling for determination of gaseous toluene diisocyanate (TDI)

Fresenius' Journal of Analytical Chemistry
Yvonne NordqvistAnders Colmsjö

Abstract

An air-sampling method employing denuders coated inside with a chemisorptive stationary phase has been evaluated for analysis of the hazardous gaseous 2,4 and 2,6 isomers of toluene diisocyanate (TDI). The denuder stationary phase consisted of polydimethylsiloxane (SE-30) to which dibutylamine (DBA) was added as a reagent for derivatization of TDI. The accuracy and precision of sampling by means of denuders were shown to differ only slightly from those of the established impinger method. The denuder method was, however, also shown to be suitable for long-term measurements (up to 8 h). The limit of determination (LOD) of the method, including LC-APCI-MS-MS analysis, was found to be 1.9 microg m(-3) and 1.2 microg m(-3) for 2,4- and 2,6-TDI, respectively, for short-term measurements (15 min). Significant lower LOD was obtained for long-term measurements. This is well below the Occupational Safety and Health Administration (OSHA) 8-h TWA (time-weighted average) exposure limit, which is 40 microg m(-3) for the sum of the TDI isomers. The denuder method was also found to be robust and easy to handle. The samplers can be prepared several days before sampling with no loss in performance. The contents of denuders should, on the other h...Continue Reading

Citations

Jun 9, 2005·Analytical and Bioanalytical Chemistry·Yvonne NordqvistAnders Colmsjö
Nov 15, 2006·Analytical and Bioanalytical Chemistry·Hartmut HennekenUwe Karst
Dec 29, 2013·The Annals of Occupational Hygiene·Daniel GylestamGunnar Skarping
Oct 29, 2002·Journal of Environmental Monitoring : JEM·Christina RosenbergKerstin Engströrm
Feb 23, 2008·Journal of Chromatography. a·Ramón BatlleCarlo Crescenzi
Mar 29, 2003·Analytical and Bioanalytical Chemistry·Y NordqvistA Colmsjö

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