Comparison of development of heterotopic ossification in injured US and UK Armed Services personnel with combat-related amputations: preliminary findings and hypotheses regarding causality

The Journal of Trauma
Kate V BrownJon C Clasper

Abstract

Recent reports have documented the rate of heterotopic ossification (HO) formation in the residual limbs of combat-related amputees from the US Armed Forces injured in Operations Iraqi and Enduring Freedom. Final amputation level within the zone of injury and blast as the mechanism of injury were identified as possible risk factors for the occurrence and grade of HO. There has been no previous description of HO in combat-related amputees from the UK service personnel. The purpose of this study was to examine potential differences in the prevalence of HO between UK and US Allied Forces, with particular attention to these risk factors, patient exposures, and any treatment differences between these two groups. We reviewed the medical records and radiographs of 35 combat-related amputations from the UK and contrasted them with 213 previously reported amputations in US military personnel. We evaluated prevalence and severity of residual limb HO, Injury Severity Score (ISS), the mechanism and zone of injury, type and level of amputation, number of debridements, method of wound irrigation, presence of severe head injury and/or burns injury, use of topical negative pressure therapy and pulse lavage, number of days until wound closure, ...Continue Reading

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Citations

May 31, 2013·Journal of the Royal Army Medical Corps·Shreshth Dharm-Datta, J McLenaghan
Aug 27, 2013·The Journal of Surgical Research·Sagar DeshpandeBenjamin Levi
Mar 31, 2015·Clinical Orthopaedics and Related Research·Gabriel J PaveyThomas A Davis
Jun 2, 2015·Clinical Orthopaedics and Related Research·D S EdwardsJon C Clasper
Sep 24, 2016·Journal of Orthopaedic Trauma·Dafydd S EdwardsJonathan A Forsberg
Jul 23, 2014·Journal of Burn Care & Research : Official Publication of the American Burn Association·Abelardo MedinaEdward E Tredget
Feb 17, 2018·Computer Methods in Biomechanics and Biomedical Engineering·Naomi Rosenberg, Anthony M J Bull
Dec 2, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Neil EisensteinLiam Grover
Oct 19, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Xuhui LiuBernard Halloran
Apr 25, 2015·The Journal of Trauma and Acute Care Surgery·Jowan G Penn-BarwellJon R B Bishop
Mar 12, 2020·Journal of Wound Care·Xiangxia LiuSai R Velamuri
Nov 26, 2015·Plastic and Reconstructive Surgery·Benjamin M WheatleyIan L Valerio
Mar 21, 2018·Frontiers in Neurology·Nikita M BajwaSubburaman Mohan

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