Abstract
This clinical trial was conducted on 90 patients, aged 30-70 years, who had heart surgery. The participants were categorized into three groups. Group D received 1 µg/kg intravenous dexmedetomidine in 10 minutes, group L received 1.5 mg/kg lidocaine (1%) 90 seconds before intubation, and group F received 2 µg/kg fentanyl. The vital signs (HR, SBP, DBP, and MAP) were measured before intubation and 1st, 3rd, 5th, and 10th minutes after intubation. Data were analyzed with SPSS 19 software (chi-square, one-way ANOVA, or Kruskal-Wallis). The age (P=0.389) and gender distributions of patients were similar in all three groups. Dexmedetomidine significantly attenuated HR in the 3rd (P=0.001), 5th (P=0.001), and 10th (P=0.003) minutes after intervention. It also reduced the systolic blood pressure in the 5th (P=0.024) and 10th (P=0.006) minutes. This reduction was significantly higher in the dexmedetomidine group than that in the two other groups. In addition, dexmedetomidine caused a greater reduction in MAP in the 1st (P=0.048), 5th (P=0.0001), and 10th (P=0.0001) minutes. Discussion. All three medications were effective in controlling HR; however, dexmedetomidine caused bradycardia in the 3rd, 5th, and 10th minutes. Lidocaine resulted...Continue Reading
References
Sep 1, 1996·Journal of Clinical Anesthesia·C H KindlerA Urwyler
Oct 21, 2011·Indian Journal of Anaesthesia·Varshali M KeniyaRamesh Naphade
Nov 19, 2013·Anesthesiology and Pain Medicine·Valiallah HassaniSaeid Safari
Aug 22, 2014·International Journal of Applied & Basic Medical Research·Siddareddigari Velayudha ReddyShaik Nawaz Ahmed
Jan 1, 2013·Anesthesia, Essays and Researches·Arpita LahaSusanta Sarkar
Apr 18, 2015·Anesthesia, Essays and Researches·Arindam SarkarShilpi Awasthi
Apr 18, 2015·Anesthesia, Essays and Researches·Michell GulabaniNishi Kulshreshtha
Oct 27, 2015·Journal of Clinical and Diagnostic Research : JCDR·Sellamuthu GunalanPaneerselvam Sunder
Oct 30, 2015·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Kamlesh KumariHarpreet Singh Sandhu
May 24, 2016·Anesthesia, Essays and Researches·Shirishkumar G ChavanSurita Mandhyan
Jun 2, 2016·Anesthesiology and Pain Medicine·Sussan Soltani MohammadiAlireza Saliminia
Oct 18, 2016·Anesthesia, Essays and Researches·H D Rashmi, H K Komala
Oct 18, 2016·Anesthesia, Essays and Researches·P RaniM Trilogasundary
Oct 18, 2016·Anesthesia, Essays and Researches·Abhyuday KumarAnoop Raj Gogia
Jul 12, 2018·European Journal of Translational Myology·Mehrdad Mesbah KiaeiMasoud Ghorbanlo