Comparison of dexmedetomidine-propofol vs. fentanyl-propofol for laryngeal mask insertion

European Journal of Anaesthesiology
F UzümcügilS Ozgen

Abstract

There have been many studies to find the optimum anaesthetics to provide excellent conditions for laryngeal mask insertion. We compared the effects of dexmedetomidine administered before propofol, on laryngeal mask insertion with fentanyl combined with propofol. In all, 52 patients, ASA I-II, scheduled to have minor urological procedures were randomized into two groups. Group F received 1 microg kg(-1) fentanyl (in 10 mL normal saline) and Group D received 1 microg kg(-1) dexmedetomidine (in 10 mL normal saline). We used 1.5 mg kg(-1) propofol for induction and 50% N2O and 1.5% sevoflurane in oxygen for maintenance. We observed jaw mobility (1: fully relaxed; 2: mild resistance; 3: tight but opens; 4: closed), coughing or movement (1: none; 2: one or two coughs; 3: three or more coughs; 4: bucking/movement) and other events such as spontaneous ventilation, breath holding, expiratory stridor and lacrimation. In each category, scores <2 were acceptable for laryngeal mask insertion. More patients developed apnoea and their apnoea times were longer in Group F than Group D (P < 0.001). Respiratory rates increased in Group D (P < 0.001). Adverse events during laryngeal mask insertion were similar. The reductions in systolic and mean ...Continue Reading

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Citations

May 15, 2010·The Kaohsiung Journal of Medical Sciences·Volkan HanciIşil Ozkoçak Turan
Feb 2, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Laila MakaryBrian Robertson
Sep 12, 2014·Acta Anaesthesiologica Scandinavica·H J Kwak, J Y Kim
Nov 26, 2009·The Annals of Pharmacotherapy·Anthony T GerlachJoseph F Dasta
Dec 30, 2017·Anesthesia, Essays and Researches·Leah R GeorgeSarah Ninan

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