Comparison of Diagnostic Accuracy and Impact of Magnetic Resonance Imaging and Colonoscopy for the Management of Crohn's Disease

Journal of Crohn's & Colitis
O García-BoschJulián Panés

Abstract

The objective of the current study was to compare two patient assessment strategies using colonoscopy and MRI alternatively as first- and second-line examinations. Clinical data, endoscopy and magnetic resonance imaging (MRI) examinations of 100 patients diagnosed with ileocolonic Crohn's disease (CD) performed within 1 week were blindly reviewed by 4 clinical investigators. Two investigators evaluated MRI followed by colonoscopy for 50 cases and the same examinations in reverse order for another 50 cases; the other 2 investigators evaluated the same cases switching the order of examinations. The assessments included the likelihood of the presence of inflammation, stenosis, fistula and abscess, and therapeutic recommendations. Information from the first examination was considered sufficient for management in 80% of cases for MRI and only 34% of cases for colonoscopy (p < 0.001). Adding MRI to the information from colonoscopy changed the clinicians' confidence grade in a higher proportion of patients than adding colonoscopy to information from MRI for the diagnosis of disease activity (10 vs 4%, p = 0.03), stenosis (25 vs 9%, p < 0.001), fistula (31 vs 0%, p < 0.001) and internal abscess (27 vs 0%, p < 0.001). Indications for an...Continue Reading

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Citations

Jul 8, 2014·PloS One·Chloé MelchiorCéline Savoye-Collet
Jun 18, 2016·Current Gastroenterology Reports·Jordi Rimola, Julián Panés
Sep 8, 2016·Journal of Gastroenterology·Jordi RimolaJulián Panés
Oct 23, 2018·Alimentary Pharmacology & Therapeutics·Jordi RimolaJulián Panés
Dec 13, 2016·Journal of Magnetic Resonance Imaging : JMRI·Gauraang BhatnagarStuart A Taylor
Oct 3, 2018·Digestive Diseases and Sciences·Patrick AlthoffThorsten Brechmann
Sep 10, 2019·World Journal of Gastroenterology : WJG·Davide BelliniAndrea Laghi

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